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Article
Cartilage repair: A review of Stanmore experience in the treatment of osteochondral defects in the knee with various surgical techniques
Articular cartilage damage in the young adult knee, if left untreated, it may proceed to degenerative osteoarthritis and is a serious cause of disability and loss of function. Surgical cartilage repair of an o...
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Article
Collagen-covered versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a comparison of tourniquet times
We have compared tourniquet times of two techniques of autologous chondrocyte implantation (ACI). Seventy-three patients underwent the collagen covered ACI technique (ACI-C) and 63 patients underwent the matri...
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Article
The use of autologous chondrocyte implantation following and combined with anterior cruciate ligament reconstruction
We report our experience of using autologous chondrocyte implantation (ACI) to treat osteochondral defects of the knee in combination with anterior cruciate ligament (ACL) reconstruction. The outcome of sympto...
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Article
A hydrophylic polymer system enhanced articular cartilage regeneration in vivo
This study describes a new method for the repair of large articular cartilage defects in the knee joint and compares the effect of two polymer systems on the quality of the repair tissue. The two systems are a...
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Article
The growth of chondrocytes using Gelfoam® as a biodegradable scaffold
Successful articular cartilage resurfacing must overcome several problems: the implant must easily fit the defect, it must be stable within the defect before full incorporation of repair tissue has occurred, a...
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Article
A simple method of cartilage regeneration using a new polymerizing system: ultrastructural characteristics of the repair tissue
The ultrastructural characteristics of the repair tissue in large articular cartilage defects, filled with a heterocyclic polymerizing system were studied using transmission electron microscopy (TEM) and energ...
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Article
Characterization of the repair tissue in articular cartilage defects using silver-enhanced colloidal gold immunostaining
The newly developed silver-enhanced colloidal gold staining method was used in a rabbit model to characterize the repair tissue in large articular cartilage defects filled with a heterocyclic methacrylate poly...
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Article
Gewrichtsproprioceptie in gezonde, osteoartritische en vervangen knieën
Neuropathische gewrichten zijn bij een verscheidenheid van aandoeningen aangetroffen, zoals diabetes, syringomyelie en congenitale afwezigheid van pijn. Waar Charcot-gewrichten aanwezig zijn, worden neurologis...
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Chapter
Heptylphysostigmine — Novel Acetylcholinesterase Inhibitor: Biochemical and Behavioral Pharmacology
The discovery in the 1970’s that choline acetyltransferase (ChAT) is markedly reduced in the brains of patients with Alzheimer’s disease (AD) compared with those of age-matched controls (Bowen et al., 1976) pr...
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Chapter and Conference Paper
Implants of Frozen and Decalcified Allogeneic Bone in Rats
A standardized non-healing bone defect, described by Siegel et al. (1972), was performed on rat femora. The defect consisting of the midsection of the femur was immobilized by internal fixation, using an omega...
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Article
Morphine Antagonism
Two years ago, a report was published1 by us of some aspects of the pharmacology of morphine. It described what we consider to be a very remarkable example of drug antagonism. Dogs narcotized to the point of unco...
