Implants of Frozen and Decalcified Allogeneic Bone in Rats

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Bone Transplantation

Abstract

A standardized non-healing bone defect, described by Siegel et al. (1972), was performed on rat femora. The defect consisting of the midsection of the femur was immobilized by internal fixation, using an omega-shaped intramedullary distraction pin. The gaps were filled by two types of allogeneic bone: (a) frozen cancellous bone (−70 °C) and (b) decalcified cortical bone (0.6 N HCl). In a control group, autologous bone grafts were used. The animals were sacrificed at 6 and 12 weeks. The samples were analysed by X rays and in histological preparations.

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© 1989 Springer-Verlag, Berlin Heidelberg

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Yde, P., Dowd, G.S.E., Bentley, G., Handelberg, F., Casteleyn, P.P., Opdecam, P. (1989). Implants of Frozen and Decalcified Allogeneic Bone in Rats. In: Aebi, M., Regazzoni, P. (eds) Bone Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83571-1_13

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  • DOI: https://doi.org/10.1007/978-3-642-83571-1_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83573-5

  • Online ISBN: 978-3-642-83571-1

  • eBook Packages: Springer Book Archive

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