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    Article

    Pharmacokinetics of dipyridamole-β-cyclodextrin complex in healthy volunteers after single and multiple doses

    Dipyridamole is a well known anti-aggregating agent characterized by poor water solubility as well as scant and variable bioavailability. Recently, the compound was complexed with β-cyclodextrin forming a mole...

    G. Ricevuti, A. Mazzone, D. Pasotti in European Journal of Drug Metabolism and Ph… (1991)

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    Article

    Effects of erdosteine on sputum biochemical and rheologic properties: Pharmacokinetics in chronic obstructive lung disease

    Erdosteine is a new thioderivative endowed with mucokinetic, mucolytic, and free-radical-scavenging properties. This study evaluated (in a double-blind design vs. placebo) its efficacy on biochemical and rheol...

    C. F. Marchioni, M. Moretti, M. Muratori, M. C. Casadei, P. Guerzoni, R. Scuri in Lung (1990)

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    Article

    Neuroleptic-induced prolactin rise: Influence of pharmacological alterations of different neurotransmitter systems

    Oral administration of 2 neuroleptic drugs, haloperidol and LR511 induced in male rats a marked, dose-dependent and sustained rise of plasma prolactin.

    Tea Chieli, Daniela Cocchi, G. B. Fregnan, E. E. Müller in Experientia (1980)

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    Article

    10-Methoxyergoline derivatives asα-adrenergic blocking agents

    Vengono descritte le attività adrenolitiche di una nuova classe di derivati dell'ergolina di formula generale IV. Uno di questi composti (No. 20) è stato esaminato su diversi reattivi biologici che hanno messo...

    G. Arcari, L. Bernardi, G. Bosisio, S. Coda, G. B. Fregnan, A. H. Glässer in Experientia (1972)

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    Article

    Abstracts

    F. G. Van den Brink, Andrea Vaccari in Naunyn-Schmiedebergs Archiv für Pharmakolo… (1971)

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    Article

    Structure-activity relationship of various acyl derivatives of 6-methyl-8β-aminomethyl-10α-ergoline (dihydrolysergamine)

    Alcuni acil derivati dell'ergoline hanno dimostrato notevoli proprietà ossitociche, adrenolitiche ed anti-5-idrossitriptaminiche, (anti-5-HT). In particolare l'acetil e l'isobutirril diidrolisergamina possiedo...

    G. B. Fregnan, A. H. Glässer in Experientia (1968)

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    Chapter and Conference Paper

    Cardiovascular Actions of Physalaemin

    Physalaemin and eledoisin and perhaps substance P belong to a group of peptides having similar pharmacological actions (Bertaccini et al., 1965a,b) both in vitro and in vivo. In vivo, these peptides affect the...

    A. H. Glasser, G. B. Fregnan in Hypotensive Peptides (1966)