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Article
Neuroinflammation, immune system and Alzheimer disease: searching for the missing link
Due to an increasingly aging population, Alzheimer disease (AD) represents a crucial issue for the healthcare system because of its widespread prevalence and the burden of its care needs. Several hypotheses on...
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Article
Bioethics, the Surviving Sepsis Campaign and the industry
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Article
Severe acute cerebrovascular disease revealing hepatitis C virus infection: effectiveness of alpha-interferon
It is well known that hepatitis C virus (HCV) can be associated with cryoglobulinemia- induced central and peripheral nervous system disorders, even without significant hepatic damage. The effectiveness of al...
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Development of a Method to Use Boron Neutron Capture Therapy for Diffused Tumours of Liver (Taormina Project)
The research informing this paper is based on the idea to treat, by BNCT, the human liver metastases by neutron irradiation of the organ outside the patient. The program, originally proposed by groups of surge...
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Article
Pharmacokinetics of dipyridamole-β-cyclodextrin complex in healthy volunteers after single and multiple doses
Dipyridamole is a well known anti-aggregating agent characterized by poor water solubility as well as scant and variable bioavailability. Recently, the compound was complexed with β-cyclodextrin forming a mole...
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Article
Peptide opioids and morphine effects on inflammatory process
Morphine was found to inhibit human granulocyte aggregation and ATP, thromboxane B2 (TxB2), and leukotriene B4 (LTB4) secretion during cell aggregation. None of the opioid peptides tested [(d-Ala2,d-Leu5)-enkepha...
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Article
In vivo andin vitro HeNe laser effects on phagocyte functions
The goal of this work was to evaluate the effect of helium-neon (HeNe) laser irradiation on immunocompetent cells. We used the in vivo skin window method and in vitro granulocyte function tests. The study of c...
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Effect of piroxicam therapy on granulocyte function and granulocyte elastase concentration in peripheral blood and synovial fluid of rheumatoid arthritis patients
The effect of piroxicam therapy (20 mg/day for 15 days) on various polymorphonuclear granulocyte (PMN) responses and on PMN elastase concentration was investigated in nine patients with active rheumatoid arthr...
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Article
Erythroblastic transformation of chronic granulocytic leukemia
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Abnormal splenic uptake of red cells in long-lasting iron deficiency anemia due to self-induced bleeding (factitious anemia)
Die Erythrokinetic wurde bei 6 Patienten mit “anemia factitia” untersucht. Bei allen Patienten konnte sowohl Eisenmangel wie auch Blutverlust nach Selbstverletzung nachgewiesen werden. Außerdem wurde eine früh...
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Article
Adriamycin: Toxicity data
Si è studiato sperimientalmente la tossicologia acuta e subacuta dell'adriamicina, un nuovo antibiotico antitumorale con struttura simile a quella della daunomicina, rilevandone l'attività depressiva sulla rip...
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Article
Effect of ergocornine on the luteal 20α-hydroxysteroid dehydrogenase in pseudopregnant and pregnant rats
Trattando ratte gravide o pseudogravide con ergocornina si può osservare la comparsa dell'attivitá 20α-idrossisteroide-deidrogenasica nei corpi lutei rispettivamente gravidici o pseudogravidici nei quali tale att...