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Article
Long-term anti-tumour necrosis factor therapy reverses the progression of carotid intima–media thickness in female patients with active rheumatoid arthritis
The objective of the study is to evaluate the effect of TNF inhibition on carotid thickness over a 2-year period. 144 women with RA diagnosed according to ACR criteria, without clinical evidence of cardiac and...
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Article
Effect of dual blockade of renin–angiotensin system on TGFβ1 and left ventricular structure and function in hypertensive patients
The effects of 24 weeks losartan and ramipril treatment, both alone and in combination, on left ventricular mass (LVM), circulating transforming growth factor β1 (TGFβ1), procollagen type I (PIP) and III (PIIIP),...
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Article
Effects of moderate Sicilian red wine consumption on inflammatory biomarkers of atherosclerosis
The aim of the study is to evaluate the effect of moderate Sicilian red wine consumption on cardiovascular risk factors and, in particular, on some inflammatory biomarkers.
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Article
Left ventricular filling abnormalities and obesity-associated hypertension: relationship with overproduction of circulating transforming growth factor β1
This study has been designed to evaluate the relationship among transforming growth factor β1 (TGFβ1) and some measurements of diastolic function in a population of hypertensive subjects with normal left ventricu...
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Article
Relationship between transforming growth factor β1 and progression of hypertensive renal disease
In this study the role of circulating transforming growth factor β1 (TGFβ1) on progression of renal hypertensive disease has been investigated. Fifty consecutive outpatients with essential hypertension were en...
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Article
Non lipid, dose-dependent effects of pravastatin treatment on hemostatic system and inflammatory response
Objectives: The aim of the present study was to evaluate the effects of pravastatin treatment on lipid, inflammation, and coagulation parameters in patients suffering from myocardial inf...
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Chapter
A survey on apolipoprotein A-I and B: the CNR study
We report on a survey of apolipoprotein A-I and B measurements among 11 laboratories using a lyophilized serum to be evaluated for its possible use as “reference serum” in a large prospective study. Using a si...
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Chapter
Effects of Antihypertensive Treatment on Peripheral Flow of the Lower Limbs
The clinical pattern determined in subjects that undergo a high and prolonged pressure regime is defined as “hypertensive disease”.
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Chapter
Platelet Activity and Blood Lipid Changes in Diabetes Mellitus
An altered platelet function can often be found in diabetes mellitus (2, 3, 4, 10, 13, 16, 17, 23, 24). Several studies have pointed towards an increased sensitivity of platelets to ADP induced aggregation (3,...
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Chapter
Factor VIII and Antithrombin III in Atherosclerosis Obliterans of the Lower Limbs
In the multifactorial pathogenesis of atherosclerosis (the W.H.O. gives a list of about forty risk factors) recent acquisitions have allowed to determine in part the role carried out by the term “haemocoagulat...
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Chapter
Platelet Aggregation, Coagulation and Fibrinolysis at Rest and after Bicycle Ergometer Test in CHD
Several observers have suggested that a dysfunction of dynamic balance between platelet aggregation, coagulation and fibrinolysis may be a factor in the pathogenesis of atherosclerosis. This dysfunction, presu...
