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Article
Open AccessDefining the optimal target-to-background ratio to identify positive lymph nodes in prostate cancer patients undergoing robot-assisted [99mTc]Tc-PSMA radioguided surgery: updated results and ad interim analyses of a prospective phase II study
Prostate-specific membrane antigen radioguided surgery (PSMA-RGS) might identify lymph node invasion (LNI) in prostate cancer (PCa) patients undergoing extended pelvic lymph node dissection (ePLND). The optima...
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Article
Intraoperative image-guidance during robotic surgery: is there clinical evidence of enhanced patient outcomes?
To date, the benefit of image guidance during robot-assisted surgery (IGS) is an object of debate. The current study aims to address the quality of the contemporary body of literature concerning IGS in robotic...
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Chapter
Posterior Approach for Robot-Assisted Radical Prostatectomy
The posterior trans-peritoneal approach for robot-assisted radical prostatectomy (RARP) in prostate cancer (PCa) patients has been widely adopted over time, where the first minimally invasive radical prostatec...
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Article
Differences in future life expectancy of testicular germ-cell tumor patients vs. age-matched male population-based controls
It is unknown whether five-year overall survival (OS) differs and to what extent between testicular germ-cell tumor (TGCT) patients and age-matched male population-based controls.
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Article
Open AccessRegional differences in clear cell metastatic renal cell carcinoma patients across the USA
To test for regional differences in clear cell metastatic renal cell carcinoma (ccmRCC) patients across the USA.
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Article
Impact of prostate MRI central review over the diagnostic performance of MRI-targeted biopsy: should we routinely ask for an expert second opinion?
There is substantial variability in multiparametric MRI (mpMRI) protocols and inter-readers’ agreement. We tested the effect of a central mpMRI review on the detection of clinically significant PCa (csPCa) in ...
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Article
Open AccessThe impact of a second MRI and re-biopsy in patients with initial negative mpMRI-targeted and systematic biopsy for PIRADS ≥ 3 lesions
To evaluate the proportions of detected prostate cancer (PCa) and clinically significant PCa (csPCa), as well as identify clinical predictors of PCa, in patients with PI-RADS > = 3 lesion at mpMRI and initial...
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Article
Characteristics of incidental prostate cancer in the United States
Data regarding North-American incidental (cT1a/b) prostate cancer (PCa) patients is scarce. To address this, incidental PCa characteristics (age, PSA values at diagnosis, Gleason score [GS]), subsequent treatm...
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Article
Oncological and perioperative outcomes of surgery with or without metastasis-directed therapy as part of a multimodal treatment in men with de-novo oligometastatic prostate cancer
To investigate the feasibility, safety, and oncological outcomes of Radical Prostatectomy (RP; either Robot-Assisted [RARP] or Open RP [ORP]) in oligometastatic prostate cancer (omPCa). Additionally, we assess...
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Article
Differences in overall survival of T2N0M0 bladder cancer patients vs. population-based controls according to treatment modalities
It is unknown to what extent overall survival (OS) of organ-confined (T2N0M0) urothelial carcinoma of the urinary bladder (UCUB) patients differs from age- and sex-matched population-based controls, especially...
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Article
Open AccessRisk and predictors of adverse pathology after radical prostatectomy in patients diagnosed with IUSP 1–2 prostate cancer at MRI-targeted biopsy: a multicenter analysis
Although active surveillance (AS) is recommended for low- to favorable intermediate-risk prostate cancer (PCa), risk of upgrading at radical prostatectomy (RP) is not negligible. Available studies based on sys...
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Article
Effect of inguinal lymph node dissection in lymph node negative patients with squamous cell carcinoma of the penis
The survival benefit of inguinal lymph node dissection (ILND) vs no ILND in patients with squamous cell carcinoma of the penis (SCCP) and the absence of lymph node invasion is unclear. We addressed this uncert...
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Article
Assessing the need for systematic biopsies in addition to targeted biopsies according to the characteristics of the index lesion at mpMRI. Results from a large, multi-institutional database
We hypothesized that systematic biopsies (SBx) value for clinically significant PCa (csPCa) detection, in addition to mpMRI targeted biopsies (TBx), may vary significantly according to mpMRI index lesion (IL) ...
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Chapter
The Role of Immunotherapy as Bladder-Sparing Solution for Muscle-Invasive and Non-muscle-Invasive Bladder Cancer: Current Status and Future Perspectives
Bladder cancer (BCa) management has rapidly changed over the past several years after a long period in which the treatment landscape of this disease was remarkably stagnant. Although radical cystectomy (RC) is...
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Article
Optimizing prostate-targeted biopsy schemes in men with multiple mpMRI visible lesions: should we target all suspicious areas? Results of a two institution series
To assess the diagnostic added value of sampling secondary lesions at prostate mpMRI (SL) in addition to index lesion (IL) in detecting significant prostate cancer (csPCa) when also systematic biopsy (SBx) is ...