-
Article
Open AccessCRUSTY: a versatile web platform for the rapid analysis and visualization of high-dimensional flow cytometry data
Flow cytometry (FCM) can investigate dozens of parameters from millions of cells and hundreds of specimens in a short time and at a reasonable cost, but the amount of data that is generated is considerable. Co...
-
Article
Open AccessArena-Idb: a platform to build human non-coding RNA interaction networks
High throughput technologies have provided the scientific community an unprecedented opportunity for large-scale analysis of genomes. Non-coding RNAs (ncRNAs), for a long time believed to be non-functional, ar...
-
Article
Open AccessA platform independent RNA-Seq protocol for the detection of transcriptome complexity
Recent studies have demonstrated an unexpected complexity of transcription in eukaryotes. The majority of the genome is transcribed and only a little fraction of these transcripts is annotated as protein codin...
-
Article
Open AccessBEAT: Bioinformatics Exon Array Tool to store, analyze and visualize Affymetrix GeneChip Human Exon Array data from disease experiments
It is known from recent studies that more than 90% of human multi-exon genes are subject to Alternative Splicing (AS), a key molecular mechanism in which multiple transcripts may be generated from a single gen...
-
Article
Open AccessGIDL: a rule based expert system for GenBank Intelligent Data Loading into the Molecular Biodiversity database
In the scientific biodiversity community, it is increasingly perceived the need to build a bridge between molecular and traditional biodiversity studies. We believe that the information technology could have a...
-
Article
Open AccessGene analogue finder: a GRID solution for finding functionally analogous gene products
To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in and their cellular localization using a ver...
-
Article
Open Accessp53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlap** functions in pivotal cellular processes such as DNA synthesis and repair, growth arrest, apoptosis, genom...
-
Article
Open AccessMitoRes: a resource of nuclear-encoded mitochondrial genes and their products in Metazoa
Mitochondria are sub-cellular organelles that have a central role in energy production and in other metabolic pathways of all eukaryotic respiring cells. In the last few years, with more and more genomes being...
