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  1. No Access

    Article

    Cell Cycle Arrest Protein CDKN2C Is Not an HBV Host Factor

    Guiwen Guan, Liwei Zheng, **gyuan **, **ngwen Yang, **angmei Chen… in Virologica Sinica (2021)

  2. No Access

    Chapter

    HBV Genome and Life Cycle

    Chronic hepatitis B virus (HBV) infection remains to be a serious threat to public health and is associated with many liver diseases including chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular car...

    Jie Wang, Hongxin Huang, Yongzhen Liu, Ran Chen, Ying Yan… in Hepatitis B Virus Infection (2020)

  3. No Access

    Article

    TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy

    Treatment failure in high risk neuroblastoma is largely due to development of chemoresistance. NF-κB activation is one of the resistance mechanisms for cancer cells to escape from chemotherapy-induced cell-dea...

    Yihui Fan, ** Cheng, Sanjeev A. Vasudevan, Roma H. Patel, Li Liang, **n Xu… in Apoptosis (2013)

  4. No Access

    Article

    Antigenicity, animal protective effect and genetic characteristics of candidate vaccine strains of enterovirus 71

    Enterovirus 71 (EV71) is one of the major causative agents of hand, foot and mouth disease. Recently, several EV71 inactivated vaccine candidates have been development in mainland China. To compare the antigen...

    Qunying Mao, Nan Li, **ang Yu, **n Yao, Fengxiang Li, Fengmin Lu… in Archives of Virology (2012)

  5. Article

    Open Access

    Characteristics and PD-1 expression of peripheral CD4+CD127loCD25hiFoxP3+ Treg cells in chronic HCV infected-patients

    Both regulatory T cells (Tregs) and PD-1/PD-L1 pathway were critically involved in HCV viral persistence. However, the association between them was not well investigated. Herein, we aimed to investigate the di...

    Tao Shen, Jiajia Zheng, Hua Liang, Chunhui Xu, **angmei Chen… in Virology Journal (2011)

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  6. Article

    Open Access

    PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patients

    Tight correlation between host circulating CD8+ T cell-mediated immune response and control of viral replication is classical characteristic of long-term HCV infection. CD8+ T cell maturation/activation marker...

    Tao Shen, Jiajia Zheng, Chunhui Xu, Jia Liu, Weidong Zhang, Fengmin Lu… in Virology Journal (2010)

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  7. No Access

    Article

    Distributional characteristics of CD25 and CD127 on CD4+ T cell subsets in chronic HCV infection

    Attenuated CD4+ T-cell-mediated immune responses are involved in persistence of HCV infection, but the mechanism remains undefined. In this study, the proportions of CD4+ T cell subsets, naïve, central memory,...

    Tao Shen, **angmei Chen, Qiang Xu, Fengmin Lu, Shuang Liu in Archives of Virology (2010)