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Article
Open AccessGPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models
For many solid tumors, immune checkpoint blockade therapy has become first line treatment, yet a large proportion of patients with immunologically cold tumors do not benefit due to the paucity of tumor infiltr...
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Article
Open AccessThe GPR171 pathway suppresses T cell activation and limits antitumor immunity
The recently identified G-protein-coupled receptor GPR171 and its ligand BigLEN are thought to regulate food uptake and anxiety. Though GPR171 is commonly used as a T cell signature gene in transcriptomic stud...
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Chapter and Conference Paper
S-State Dependence of Misses in the OEC Probed by EPR Spectroscopy of Individual S-States
We have analyzed S-transition dependent miss fractions in the S-cycle using the S1 and S3 split EPR signals together with the S2 state multiline EPR signal. We demonstrate that quantification of the S1 and S3 sta...