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Strategies to identify hepatitis C virus infection in patients receiving anticancer therapy: a cross-sectional study
Optimal hepatitis C virus (HCV) screening strategies for cancer patients have not been established. We compared the performance of selective HCV screening strategies.
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Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
Autologous chimeric antigen receptor (CAR) T cell therapies targeting CD19 have high efficacy in large B cell lymphomas (LBCLs), but long-term remissions are observed in less than half of patients, and treatme...
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Open AccessLncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2
Mantle cell lymphoma (MCL) is considered an aggressive subtype of non-Hodgkin’s lymphoma with variable treatment responses. There is an urgent need to identify novel markers with prognostic and therapeutic val...
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Open AccessTargeting Wnt pathway in mantle cell lymphoma-initiating cells
Mantle cell lymphoma (MCL) is an aggressive and incurable form of non-Hodgkin’s lymphoma. Despite initial intense chemotherapy, up to 50 % of cases of MCL relapse often in a chemoresistant form. We hypothesize...
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Open AccessCD74 interferes with the expression of fas receptor on the surface of lymphoma cells
Resistance to Fas-mediated apoptosis limits the efficacy of currently available chemotherapy regimens. We identified CD74, which is known to be overexpressed in hematological malignancies, as one of the factor...
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Article
Open AccessThe peptide derived from the Ig-like domain of human herpesvirus 8 K1 protein induces death in hematological cancer cells
Although significant progress has been made in the treatment of lymphomas, many lymphomas exhibit resistance to cell death, suggesting a defective Fas signaling, which remains poorly understood. We previously ...
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Urinary proteins with pro-apoptotic and antitumor activity
Analysis of the protein composition of urine has been the subject of much research that has captured the interest of scientific groups over the years. A number of factors have been isolated from urine that pos...
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Chapter
Immunopathogenesis of Kaposi’s Sarcoma
Kaposi’s sarcoma (KS) is a proliferative disease of vascular origin and is the most frequent tumor of human immunodeficiency virus type 1 (HIV-1)-infected individuals, particularly of homosexual and bisexual m...
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Kaposi's sarcoma in pregnant women
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Correction: Tumorigenesis and metastasis of neoplastic Kaposiᤙs sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone
Nature 375, 64-68 (1995) DUE to a computer mounting error the same four figure parts in Fig. 2C (c, /, g, and h) were inadvertently submitted. The correct Fig. 1C is shown. In the legend to Fig. 2C where it re...
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Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone
KAPOSI'S sarcoma (KS) occurs more often in men than in women and HIV-l-associated KS has a high occurrence in homosexual men (over 30%). Most cultures of KS tumours yield cells with properties of hyperplastic ...
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An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein
Post-transcriptional regulation of genes important in iron metabolism, ferritin and the transferrin receptor (TfR), is achieved through regulated binding of a cytosolic protein, the iron-responsive element bin...
