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Article
Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells
Neutrophil elastase (NE) is an innate immune cell-derived inflammatory mediator that we have shown increases the presentation of tumor-associated peptide antigens in breast cancer. In this study, we extend the...
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Article
Open AccessThe peptide derived from the Ig-like domain of human herpesvirus 8 K1 protein induces death in hematological cancer cells
Although significant progress has been made in the treatment of lymphomas, many lymphomas exhibit resistance to cell death, suggesting a defective Fas signaling, which remains poorly understood. We previously ...
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Article
Open AccessSomatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells
opioid and somatostatin receptors (SSTRs) that can assemble as heterodimer were individually reported to modulate malignant cell proliferation and to favour apoptosis. Materials and methods: SSTRs and opioid r...