5 Result(s)
within
Felipe Samaniego
Cancer Research
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Article
Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
Autologous chimeric antigen receptor (CAR) T cell therapies targeting CD19 have high efficacy in large B cell lymphomas (LBCLs), but long-term remissions are observed in less than half of patients, and treatme...
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Article
Open AccessTargeting Wnt pathway in mantle cell lymphoma-initiating cells
Mantle cell lymphoma (MCL) is an aggressive and incurable form of non-Hodgkin’s lymphoma. Despite initial intense chemotherapy, up to 50 % of cases of MCL relapse often in a chemoresistant form. We hypothesize...
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Article
Open AccessCD74 interferes with the expression of fas receptor on the surface of lymphoma cells
Resistance to Fas-mediated apoptosis limits the efficacy of currently available chemotherapy regimens. We identified CD74, which is known to be overexpressed in hematological malignancies, as one of the factor...
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Article
Open AccessThe peptide derived from the Ig-like domain of human herpesvirus 8 K1 protein induces death in hematological cancer cells
Although significant progress has been made in the treatment of lymphomas, many lymphomas exhibit resistance to cell death, suggesting a defective Fas signaling, which remains poorly understood. We previously ...
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Article
Urinary proteins with pro-apoptotic and antitumor activity
Analysis of the protein composition of urine has been the subject of much research that has captured the interest of scientific groups over the years. A number of factors have been isolated from urine that pos...
