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In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids

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  1. Article

    Open Access

    SET protein up-regulated testosterone production in the cultured preantral follicles

    We found previously that the expression of SET gene was up-regulated in polycystic ovaries. Evidences suggested that SET protein was essential for regulating both the promoter activity of CYP17A1 and the biolo...

    Boqun Xu, Lingling Gao, Yugui Cui, Li Gao in Reproductive Biology and Endocrinology (2013)

  2. Article

    Open Access

    Effect of endometrial thickness and embryo quality on live-birth rate of fresh IVF/ICSI cycles: a retrospective cohort study

    Successful implantation and delivery require both the functional embryo and receptive endometrium in assisted reproductive technology (ART) cycles. However, little is known about embryo-endometrial interaction...

    Hong Lv, **uzhu Li, Jiangbo Du, **ufeng Ling in Reproductive Biology and Endocrinology (2020)

  3. Article

    Open Access

    Large-scale analysis of de novo mutations identifies risk genes for female infertility characterized by oocyte and early embryo defects

    Oocyte maturation arrest and early embryonic arrest are important reproductive phenotypes resulting in female infertility and cause the recurrent failure of assisted reproductive technology (ART). However, the...

    Qun Li, Lin Zhao, Yang Zeng, Yan** Kuang, Yichun Guan, Biaobang Chen in Genome Biology (2023)

  4. Article

    Open Access

    Comprehensive analysis of genomic complexity in the 5’ end coding region of the DMD gene in patients of exons 1–2 duplications based on long-read sequencing

    Dystrophinopathies are the most common X-linked inherited muscle diseases, and the disease-causing gene is DMD. Exonic duplications are a common type of pathogenic variants in the DMD gene, however, 5’ end exonic...

    Jiandong Shen, Taoli Ding, Xue** Sun, Ji Yang, Yue Zhang, **g Wang in BMC Genomics (2024)