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  1. Article

    Open Access

    Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

    Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano in Nature Communications (2022)

  2. Article

    Open Access

    Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

    The diverse functions of WASP, the deficiency of which causes Wiskott-Aldrich syndrome (WAS), remain poorly defined. We generated three isogenic WAS models using patient induced pluripotent stem cells and geno...

    Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano in Nature Communications (2022)

  3. Article

    Open Access

    Non-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation

    FIP200 is an essential autophagy gene implicated in the regulation of postnatal neural progenitor/stem cells (NSCs). However, the contribution of FIP200’s canonical-autophagy function and its non-canonical fun...

    Hang Liu, Chenran Wang, Fei Yi, Syn Yeo, Michael Haas, **n Tang in Scientific Reports (2021)

  4. Article

    Open Access

    Non-dispersive infrared multi-gas sensing via nanoantenna integrated narrowband detectors

    Non-dispersive infrared (NDIR) spectroscopy analyzes the concentration of target gases based on their characteristic infrared absorption. In conventional NDIR gas sensors, an infrared detector has to pair with...

    **aochao Tan, Heng Zhang, Junyu Li, Haowei Wan, Qiushi Guo in Nature Communications (2020)

  5. Article

    Open Access

    Photodynamic therapy inhibit Fibroblast Growth Factor-10 induced keratinocyte differentiation and proliferation through ROS in Fibroblast Growth Factor Receptor-2b pathway

    5-aminolevulinic acid-photodynamic therapy (ALA-PDT) is known to be effective in several skin diseases such as acne, actinic keratoses, condyloma acuminata. However, some detailed mechanisms of ALA-PDT to trea...

    Maya Valeska Gozali, Fei Yi, Jia-an Zhang, Juan Liu, Hong-** Wu in Scientific Reports (2016)

  6. Article

    Open Access

    PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

    PTEN is a tumour suppressor frequently mutated in many types of cancers. Here we show that targeted disruption of PTEN leads to neoplastic transformation of human neural stem cells (NSCs), but not mesenchymal ...

    Shunlei Duan, Guohong Yuan, **aomeng Liu, Ruotong Ren, **gyi Li in Nature Communications (2015)

  7. No Access

    Article

    Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

    Fanconi anaemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow (BM) failure. However, the pathogenesis of FA is not fully und...

    Guang-Hui Liu, Keiichiro Suzuki, Mo Li, **g Qu, Nuria Montserrat in Nature Communications (2014)

  8. No Access

    Article

    Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

    Investigation of neural cells from post-mortem human brains and differentiated from patient-derived induced pluripotent stem cells shows that the LRRK2 mutation (G2019S) associated with familial and sporadic P...

    Guang-Hui Liu, **g Qu, Keiichiro Suzuki, Emmanuel Nivet, Mo Li, Nuria Montserrat in Nature (2012)