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Open AccessDe-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity
Oncogenic stress induces DNA damage repair (DDR) that permits escape from mitotic catastrophe and allows early precursor lesions during the evolution of cancer. SAMHD1, a dNTPase protecting cells from viral in...
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Article
Three-Dimensional Crystal Vue Imaging technology assessment of Sylvian fissures at 20–32+6 weeks’ normal gestation
Assess developmental pattern of Sylvian fissures (SF) with Three-Dimensional Crystal Vue Imaging (3D-CVI) at 20–32+6 weeks of gestation.
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High temporal-resolution transcriptome landscapes of maize embryo sac and ovule during early seed development
Here we provided a high temporal-resolution transcriptome atlas of maize embryo sac and ovule to reveal the gene activity dynamic during early seed development.
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Open AccessAuthor Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing
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Open AccessMeta-QTL analysis explores the key genes, especially hormone related genes, involved in the regulation of grain water content and grain dehydration rate in maize
Low grain water content (GWC) at harvest of maize (Zea mays L.) is essential for mechanical harvesting, transportation and storage. Grain drying rate (GDR) is a key determinant of GWC. Many quantitative trait loc...
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Open AccessWiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing
The diverse functions of WASP, the deficiency of which causes Wiskott-Aldrich syndrome (WAS), remain poorly defined. We generated three isogenic WAS models using patient induced pluripotent stem cells and geno...
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Open AccessImmunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA
Public neoantigens (NeoAgs) represent an elite class of shared cancer-specific epitopes derived from recurrently mutated driver genes. Here we describe a high-throughput platform combining single-cell transcri...
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Open AccessRNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression
Androgen receptor (AR) signaling drives prostate cancer (PC) progression. Androgen deprivation therapy (ADT) is temporally effective, whereas drug resistance inevitably develops. Abnormal expression of AR/ARV7...
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Open AccessNon-canonical function of FIP200 is required for neural stem cell maintenance and differentiation by limiting TBK1 activation and p62 aggregate formation
FIP200 is an essential autophagy gene implicated in the regulation of postnatal neural progenitor/stem cells (NSCs). However, the contribution of FIP200’s canonical-autophagy function and its non-canonical fun...
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Three-dimensional magnetic enzyme-inorganic hybrid nanocomplexes with high reusability and stability to obtain lactose-free products
Multitudinous people suffer from lactose intolerance which is bound up with lactose malabsorption. Enzymatic hydrolysis is the most common approach for the preparation of lactose-free products. The recycling o...
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Open AccessTranscriptome dynamic landscape underlying the improvement of maize lodging resistance under coronatine treatment
Lodging is one of the important factors causing maize yield. Plant height is an important factor in determining plant architecture in maize (Zea mays L.), which is closely related to lodging resistance under high...
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Open AccessNon-dispersive infrared multi-gas sensing via nanoantenna integrated narrowband detectors
Non-dispersive infrared (NDIR) spectroscopy analyzes the concentration of target gases based on their characteristic infrared absorption. In conventional NDIR gas sensors, an infrared detector has to pair with...
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Open AccessGenome-wide analysis of lncRNA and mRNA expression and endogenous hormone regulation during tension wood formation in Catalpa bungei
Phytohormones are the key factors regulating vascular development in plants, and they are also involved in tension wood (TW) formation. Although the theory of hormone distribution in TW formation is widely sup...
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Open AccessEfficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke: a multicenter, randomized, double-blind, placebo-controlled trial
Ischemic stroke is a leading cause of morbidity and mortality. Thrombolytic therapy improves disability and survival rates; however, to be effective, it must be given within 4.5 h of onset. Moreover, thromboly...
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Investigating collaboration in ubiquitous computing research
With the rapid development of mobile internet and smart devices, ubiquitous computing is experiencing a huge change. As direct progress reflection of the field, collaboration among scholars has been increasing...
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Open AccessMoS2 Nanosheets Sensitized with Quantum Dots for Room-Temperature Gas Sensors
Highly sensitive and selective room-temperature NO2 gas sensors by sensitizing MoS2 nanosheets with PbS quantum dots were demonstrated. In this device arch...
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Open AccessSIRT1 modulates cell cycle progression by regulating CHK2 acetylation−phosphorylation
Both the stress-response protein, SIRT1, and the cell cycle checkpoint kinase, CHK2, play critical roles in aging and cancer via the modulation of cellular homeostasis and the maintenance of genomic integrity....
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Open AccessConstruction of a high-density genetic map and QTL map** of leaf traits and plant growth in an interspecific F1 population of Catalpa bungei × Catalpa duclouxii Dode
Catalpa bungei is an important tree species used for timber in China and widely cultivated for economic and ornamental purposes. A high-density linkage map of C. bungei would be an efficient tool not only for ide...
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Application of Percutaneous Osteoplasty in Treating Pelvic Bone Metastases: Efficacy and Safety
Percutaneous vertebroplasty has been a good option to treat vertebral metastases. The pelvic bone is a common site of spread for many cancers. Using follow-up data for 126 patients, we evaluated the safety and...
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Correction to: Colorectal Cancer Diagnostic Algorithm Based on Sub-Patch Weight Color Histogram in Combination of Improved Least Squares Support Vector Machine for Pathological Image
The original article unfortunately contained a mistake. The corresponding author’s name should be corrected as “Yingsheng Cheng”.