Skip to main content

3 Result(s)

within Fariba Houshmand Remove this filter

and

  1. No Access

    Article

    Metformin accelerates myelin recovery and ameliorates behavioral deficits in the animal model of multiple sclerosis via adjustment of AMPK/Nrf2/mTOR signaling and maintenance of endogenous oligodendrogenesis during brain self-repairing period

    Multiple sclerosis (MS) is a devastating autoimmune disorder characterized by oligodendrocytes (OLGs) loss and demyelination. In this study, we have examined the effects of metformin (MET) on the oligodendroge...

    Nima Sanadgol, Mahmood Barati, Fariba Houshmand… in Pharmacological Reports (2020)

  2. No Access

    Article

    Metformin-induced AMPK activation stimulates remyelination through induction of neurotrophic factors, downregulation of NogoA and recruitment of Olig2+ precursor cells in the cuprizone murine model of multiple sclerosis

    Oligodendrocytes (OLGs) damage and myelin distraction is considered as a critical step in many neurological disorders especially multiple sclerosis (MS). Cuprizone (cup) animal model of MS targets OLGs degener...

    Fariba Houshmand, Mahmood Barati… in DARU Journal of Pharmaceutical Sciences (2019)

  3. No Access

    Article

    Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells

    Selegiline, the irreversible inhibitor of monoamine oxidase B (MAO-B), is currently used to treat Parkinson’s disease. However, the mechanism of action of selegiline is complex and cannot be explained solely b...

    Shabnam Bakhshalizadeh, Fariba Esmaeili… in In Vitro Cellular & Developmental Biology … (2011)