14 Result(s)

Article

Stereotactic radioablation for the treatment of ventricular tachycardia: preliminary data and insights from the STRA-MI-VT phase Ib/II study

We present the preliminary results of the STRA-MI-VT Study (NCT04066517), a spontaneous, phase Ib/II study, designed to prospectively test the safety and efficacy of stereotactic body radiotherapy (SBRT) in pa...

Corrado Carbucicchio, Daniele Andreini… in Journal of Interventional Cardiac Electrop… (2021)

Article

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants

The relationship between intake of saturated fats and subclinical atherosclerosis, as well as the possible influence of genetic variants, is poorly understood and investigated. We aimed to investigate this rel...

Federica Laguzzi, Buamina Maitusong, Rona J. Strawbridge… in Scientific Reports (2021)

Article

Alcohol consumption in relation to carotid subclinical atherosclerosis and its progression: results from a European longitudinal multicentre study

The association between alcohol consumption and subclinical atherosclerosis is still unclear. Using data from a European multicentre study, we assess subclinical atherosclerosis and its 30-month progression by...

Federica Laguzzi, Damiano Baldassarre, Fabrizio Veglia… in European Journal of Nutrition (2021)

Article

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals

Understanding why individuals with severe mental illness (Schizophrenia, Bipolar Disorder and Major Depressive Disorder) have increased risk of cardiometabolic disease (including obesity, type 2 diabetes and c...

Rona J. Strawbridge, Keira J. A. Johnston, Mark E. S. Bailey… in Scientific Reports (2021)

Article

Prognostic impact of admission high-sensitivity C-reactive protein in acute myocardial infarction patients with and without diabetes mellitus

High-sensitivity C-reactive protein (hs-CRP) elevation frequently occurs in acute myocardial infarction (AMI) and is associated with adverse outcomes. Since diabetes mellitus (DM) is characterized by an underl...

Claudia Lucci, Nicola Cosentino, Stefano Genovese… in Cardiovascular Diabetology (2020)

Article

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study

The genes regulating circulating levels of soluble gp130 (sgp130), the antagonist of the inflammatory response in atherosclerosis driven by interleukin 6, are largely unknown. Aims of the present study were to...

Alice Bonomi, Fabrizio Veglia, Damiano Baldassarre, Rona J. Strawbridge… in Genes & Immunity (2020)

Article

Biological profile of monocyte-derived macrophages in coronary heart disease patients: implications for plaque morphology

The prevalence of a macrophage phenotype in atherosclerotic plaque may drive its progression and/or instability. Macrophages from coronary plaques are not available, and monocyte-derived macrophages (MDMs) are...

Sonia Eligini, Nicola Cosentino, Susanna Fiorelli, Franco Fabbiocchi… in Scientific Reports (2019)

Article

Genetic variation in CADM2 as a link between psychological traits and obesity

CADM2 has been associated with a range of behavioural and metabolic traits, including physical activity, risk-taking, educational attainment, alcohol and cannabis use and obesity. Here, we set out to determine wh...

Julia Morris, Mark E. S. Bailey, Damiano Baldassarre, Breda Cullen… in Scientific Reports (2019)

Article

Patho- physiological role of BDNF in fibrin clotting

Circulating levels of Brain Derived Neurotrophic Factor (BDNF) are lower in coronary heart disease (CHD) than in healthy subjects and are associated with coronary events and mortality. However, the mechanism(s...

Patrizia Amadio, Benedetta Porro, Leonardo Sandrini, Susanna Fiorelli… in Scientific Reports (2019)

Article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of...

Nora Franceschini, Claudia Giambartolomei, Paul S. de Vries… in Nature Communications (2018)

Article

The impact of pericardial approach and myocardial protection onto postoperative right ventricle function reduction

The reduction of RV function after cardiac surgery is a well-known phenomenon. It could persist up-to one year after the operation and often leads to an incomplete recovery at follow-up echocardiographic contr...

Marco Zanobini, Claudia Loardi, Paolo Poggio… in Journal of Cardiothoracic Surgery (2018)

Article

Human Genetic Evidence for Involvement of CD137 in Atherosclerosis

Atherosclerosis is an inflammatory disease and the main cause of cardiovascular disease. Inflammation promotes plaque instability and clinical disease, such as myocardial infarction, stroke and peripheral vasc...

Leif Å Söderström, Karl Gertow, Lasse Folkersen, Maria Sabater-Lleal… in Molecular Medicine (2014)

Article

Food allergy and anaphylaxis – 2061. Clinical symptoms and molecular characterization of hazelnut allergy in Italian children

Marco Albarini, Alessandro Fiocchi, Lamia Dahdah… in World Allergy Organization Journal (2013)

Article

Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries: a prospective study

Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease...

Paolo Vineis, Gerard Hoek, Michal Krzyzanowski… in Environmental Health (2007)