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Article
Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1
Overexpression of the cyclin D1 (CCND1) gene, encoding a downstream effector of mitogenic signals that plays a central role in G1 phase progression, is often found in cancerous cells. In sporadic breast cancer (B...
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Chapter and Conference Paper
Transcriptional Control of Cell Cycle Progression by Estrogenic Hormones: Regulation of Human Cyclin D1 Gene Promoter Activity by Estrogen Receptor-a
Estrogens (Es) are mitogens for breast and uterine epithelial cells, where they exert also a tumor-promoting action that appears to be directly linked to their growth promoting effects (1-3). Although during r...