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Article
Open AccessCOVID-19: Auswirkungen auf das zentrale und periphere Nervensystem
Die gesundheitlichen Auswirkungen der Coronavirus-Krankheit 2019 (COVID-19) durch die Infektion von SARS-CoV‑2 (Schweres-Akutes-Respiratorisches–Syndrom-Coronavirus 2) werden mit der Ausbreitung der Pandemie i...
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Article
A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance
In April 2013 our group published a review on predictive molecular pathology in this journal. Although only 2 years have passed many new facts and stimulating developments have happened in diagnostic molecular...
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Article
Predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance
The increasing importance of targeting drugs in the treatment of several tumor entities (breast, colon, lung, malignant melanoma (MM), lymphoma, and so on) and the necessity of a companion diagnostic (human ep...
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Article
Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas
Cells with stem cell properties have been isolated from various areas of the postnatal mammalian brain, most recently from the postnatal mouse cerebellum. We show here that inactivation of the tumor suppressor...
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Chapter and Conference Paper
Microglial activation and intracerebral hemorrhage
Microglia activate upon injury, migrate to the injury site, proliferate locally, undergo morphological and gene expression changes, and phagocytose injured and dying cells. Cytokines and proteases secreted by ...
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Article
An unusual case of a highly progressive supratentorial capillary haemangioblastoma – histopathological considerations
We describe a case of a rapidly progressive, sporadic, non-von Hippel-Lindau (VHL) disease associated supratentorial capillary haemangioblastoma. Despite the classical histopathological presentation consisting...
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Article
Correction: Corrigendum: Experimental autoimmune encephalomyelitis repressed by microglial paralysis
Nat. Med. 11, 146–152 (2005) In the original version of this article, Fig. 5b was incorrect. The correct panel appears below.
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Article
Pathogenesis of prion diseases: a progress report
Almost 20 years have passed since Stanley Prusiner proposed that the agent causing transmissible spongiform encephalopathies consists exclusively of a protein and termed it prion. A mixed balance can be drawn ...