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    Article

    Pharmacokinetics of Levodopa and Carbidopa in Rats Following Different Routes of Administration

    This study examined the pharmacokinetics of levodopa and carbidopa in the rat after different modes of administration. The drugs were given simultaneously by the intravenous, intraarterial, oral, duodenal, and...

    Eva Bredberg, Hans Lennernäs, Lennart Paalzow in Pharmaceutical Research (1994)

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    Article

    Altered Pharmacokinetics and Dynamics of Apomorphine in the Malnourished Rat: Modeling of the Composed Relationship Between Concentration and Heart-Rate Response

    The impact of malnutrition on the pharmacokinetics and pharmacodynamics (change in heart rate) of apomorphine was studied in the rat. One group of rats received a low-protein diet (0.5%) ad libitum to produce pre...

    Eva Bredberg, Lennart K. Paalzow in Pharmaceutical Research (1990)