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Article
Nature vs. Manmade: Comparing Exosomes and Liposomes for Traumatic Brain Injury
Traumatic brain injury (TBI) of all severities is a significant public health burden, causing a range of effects that can lead to death or a diminished quality of life. Liposomes and mesenchymal stem cell-deri...
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Article
Thermo in the Time of COVID-19: Using Improvisation to Foster Discussion and Translating the Experience to Online Learning
This paper covers teaching a graduate thermodynamics class as a seminar and using improvisational activities to foster community and discussion. The paper includes the experience of piloting improvisational ac...
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Article
Reporter Scaffolds for Clinically Relevant Cell Transplantation Studies
There are a number of cell therapies that are either in clinical trials or moving toward clinical trials, particularly for diseases of the retina. One of the challenges with cell therapies is tracking the stat...
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Article
Open AccessHemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model
Explosions account for 79% of combat related injuries and often lead to polytrauma, a majority of which include blast-induced traumatic brain injuries (bTBI). These injuries lead to internal bleeding in multip...
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Article
Olfactory Ensheathing Cells Promote Differentiation of Neural Stem Cells and Robust Neurite Extension
The goal of this study was to gain insight into the signaling between olfactory ensheathing cells (OECs) and neural stem cells (NSCs). We sought to understand the impact of OECs on NSC differentiation and neur...
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Article
Functional Recovery Following Spinal Cord Hemisection Mediated by a Unique Polymer Scaffold Seeded with Neural Stem Cells
A dual scaffold structure made of biodegradable polymers and seeded with neural stem cells has been developed to address the issues of spinal cord injury including axonal severance and the loss of neurons and ...
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Chapter
Angiogenesis, the Neurovascular Niche and Neuronal Reintegration After Injury
Injury to the central nervous system caused by traumatic brain and/or spinal cord injury, stroke, autoimmune and neurodegenerative diseases and hypoxia all evoke a repair process involving angio-genesis and ne...
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Chapter
Neural Tissue Engineering
Biomaterials have played a role in the nervous system as drug delivery vehicles and scaffolds. The nervous system, both the peripheral and central, are capable of repair and regeneration when the appropriate e...
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Chapter
Neural Stem Cells in and from the Spinal Cord
It had long been held that neurogenesis in the mammalian central nervous system (CNS) was largely completed by birth. This opinion held sway until the early 1960s, when cellular proliferation was discovered in...
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Protocol
Seeding Neural Stem Cells on Scaffolds of PGA, PLA, and Their Copolymers
Tissue engineering has arisen to address the extreme shortage of tissues and organs for transplantation and repair. One of the most successful techniques has been the seeding and culturing of cells on three-di...
