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Article
Open AccessResilience of females to acute blood–brain barrier damage and anxiety behavior following mild blast traumatic brain injury
Low-level blast exposure can result in neurological impairment for military personnel. Currently, there is a lack of experimental data using sex as a biological variable in neurovascular outcomes following bla...
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Article
Open AccessFractionated mitochondrial magnetic separation for isolation of synaptic mitochondria from brain tissue
While mitochondria maintain essential cellular functions, such as energy production, calcium homeostasis, and regulating programmed cellular death, they also play a major role in pathophysiology of many neurol...
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Article
Open AccessHemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model
Explosions account for 79% of combat related injuries and often lead to polytrauma, a majority of which include blast-induced traumatic brain injuries (bTBI). These injuries lead to internal bleeding in multip...
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Chapter
Mitochondrial Damage in Traumatic CNS Injury
Traumatic brain injury (TBI) is ever-present in societal issues and puts a tremendous economic burden on U.S. healthcare and affected individuals. Symptomology after TBI is sometimes subtle without outward sig...
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Protocol
Cellular Mechanisms and Behavioral Outcomes in Blast-Induced Neurotrauma: Comparing Experimental Setups
Blast-induced neurotrauma (BINT) has increased in incidence over the past decades and can result in cognitive issues that have debilitating consequences. The exact primary and secondary mechanisms of injury ha...
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Article
Open AccessEnduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury
Few preclinical studies have assessed the long-term neuropathology and behavioral deficits after sustaining blast-induced neurotrauma (BINT). Previous studies have shown extensive astrogliosis and cell death a...
