6 Result(s)
within
Eric A Stone
Human Genetics
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Article
Open AccessPhysical separation of haplotypes in dikaryons allows benchmarking of phasing accuracy in Nanopore and HiFi assemblies with Hi-C data
Most animals and plants have more than one set of chromosomes and package these haplotypes into a single nucleus within each cell. In contrast, many fungal species carry multiple haploid nuclei per cell. Rust ...
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Article
The genetics of quantitative traits: challenges and prospects
Most phenotypic variation in natural populations is attributable to multiple interacting loci, with allelic effects that are sensitive to the exact environment...
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Article
Open AccessA transcriptional network associated with natural variation in Drosophilaaggressive behavior
Aggressive behavior is an important component of fitness in most animals. Aggressive behavior is genetically complex, with natural variation attributable to multiple segregating loci with allelic effects that ...
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Article
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep
Trudy Mackay and colleagues measure sleep phenotypes in 40 wild-derived Drosophila lines, and report candidate genes and transcriptional networks associated with sleep regulation.
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Article
Systems genetics of complex traits in Drosophila melanogaster
Trudy Mackay and colleagues present a resource of 40 Drosophila melanogaster wild-derived inbred lines. The authors quantify genome-wide variation in transcript abundance for six ecologically relevant traits, cha...
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Article
Open AccessMixture modeling of transcript abundance classes in natural populations
Populations diverge in genotype and phenotype under the influence of such evolutionary processes as genetic drift, mutation accumulation, and natural selection. Because genotype maps onto phenotype by way of t...
