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Article
The genetics of quantitative traits: challenges and prospects
Most phenotypic variation in natural populations is attributable to multiple interacting loci, with allelic effects that are sensitive to the exact environment...
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Article
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep
Trudy Mackay and colleagues measure sleep phenotypes in 40 wild-derived Drosophila lines, and report candidate genes and transcriptional networks associated with sleep regulation.
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Article
Systems genetics of complex traits in Drosophila melanogaster
Trudy Mackay and colleagues present a resource of 40 Drosophila melanogaster wild-derived inbred lines. The authors quantify genome-wide variation in transcript abundance for six ecologically relevant traits, cha...