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Article
Epigenetic programming underpins B cell dysfunction in human SLE
Systemic lupus erythematosus (SLE) is characterized by the expansion of extrafollicular pathogenic B cells derived from newly activated naive cells. Although these cells express distinct markers, their epigene...
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Article
Open AccessATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells
Biobanking is a widespread practice for storing biological samples for future studies ranging from genoty** to RNA analysis. However, methods that probe the status of the epigenome are lacking. Here, the fra...
