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  1. Article

    Open Access

    Leveraging the histidine kinase-phosphatase duality to sculpt two-component signaling

    Bacteria must constantly probe their environment for rapid adaptation, a crucial need most frequently served by two-component systems (TCS). As one component, sensor histidine kinases (SHK) control the phospho...

    Stefanie S. M. Meier, Elina Multamäki, Américo T. Ranzani in Nature Communications (2024)

  2. No Access

    Protocol

    Multimodal Control of Bacterial Gene Expression by Red and Blue Light

    By applying sensory photoreceptors, optogenetics realizes the light-dependent control of cellular events and state. Given reversibility, noninvasiveness, and exquisite spatiotemporal precision, optogenetic app...

    Stefanie S. M. Meier, Elina Multamäki, Américo T. Ranzani in Synthetic Biology (2024)

  3. Article

    Open Access

    Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling

    Bacterial phytochrome photoreceptors usually belong to two-component signaling systems which transmit environmental stimuli to a response regulator through a histidine kinase domain. Phytochromes switch betwee...

    Elina Multamäki, Rahul Nanekar, Dmitry Morozov, Topias Lievonen in Nature Communications (2021)