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Article
The healthy core metabolism: A new paradigm for primary preventive nutrition
Research in preventive nutrition aims at elucidating mechanism by which our diet helps us to remain in good health through optimal physiological functions. However, despite decades of accumulated data in human...
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Article
Open AccessDoes aging affect the immune status? A comparative analysis in 300 healthy volunteers from France, Austria and Spain
As the European population is getting older, there is growing need in scientific data on how to achieve healthy and successful aging. A decline in immune function with age is unanimously supported by many epid...
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Article
Open AccessNeutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects
The immune system gradually deteriorates with age and nutritional status is a major factor in immunosenescence. Of the many nutritional factors implicated in age-related immune dysfunction, vitamin A may be a ...
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Article
Antioxidant status of elite athletes remains impaired 2 weeks after a simulated altitude training camp
It has been shown that the antioxidant status was altered by the “live high-train low” (LHTL) method, however, no information is available regarding the antioxidant restoration during the recovery period.
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Article
Thirteen days of “live high–train low” does not affect prooxidant/antioxidant balance in elite swimmers
We investigated the impact of 13 days of “living high–training low” (LHTL) on the antioxidant/prooxidant balance in elite endurance swimmers. Eighteen elite swimmers from the French Swimming Federation were su...
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Article
Comparison of lycopene and tomato effects on biomarkers of oxidative stress in vitamin E deficient rats
Cohort studies suggested that individuals with higher intake of tomatoes and tomato products have a lower risk of degenerative diseases. Lycopene, an antioxidant and antiproliferative carotenoid, has been hypo...
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Article
Preferential response of glutathione-related enzymes to folate-dependent changes in the redox state of rat liver
Oxidative stress likely constitutes an important contributing factor in the onset of degenerative diseases associated with folate deficiency. Direct, as well as homocysteine-linked, antioxidant properties of f...
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Article
Entire potato consumption improves lipid metabolism and antioxidant status in cholesterol-fed rat
Vegetables and fruits are rich sources of a variety of nutrients, including vitamins (E and C), trace minerals, and dietary fibers, and many other classes of biologically active compounds such as carotenoids a...
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Article
Growth Arrest and Decrease of α-SMA and Type I Collagen Expression by Palmitic Acid in the Rat Hepatic Stellate Cell Line PAV-1
Liver fibrosis is characterized by an activation of hepatic stellate cells (HSC). During primary culture HSC evolve from a quiescent into an activated phenotype which is characterized by α-smooth muscle actin ...
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Article
Effect of carrot intake on cholesterol metabolism and on antioxidant status in cholesterol-fed rat
Vegetables are major dietary sources of fibers and antioxidants such as carotenoids, polyphenols and vitamin C which contribute to explain their protective effects against cardiovascular diseases.
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Article
Protective effect of calcium deficiency on the inflammatory response in magnesium-deficient rats
Background: Previous studies indicated that dietary Mg-deficiency in rats results in a marked pro-inflammatory effect. Since magnesium (Mg) frequently acts as a natural calcium (Ca) antagonist, the possibility e...