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Article
Open AccessVolatile Organic Compounds Detected in Amniotic Fluid of Women During Normal Pregnancy
Exposure to volatile organic compounds (VOCs) during the fetal period may induce negative effects on children’s health (e.g. increased risk of low birth weight and imbalanced development). Whereas VOCs have be...
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Article
Correction to: 25-Hydroxyvitamin D potentializes extracellular cathelicidin release from human PBMC stimulated ex vivo with either bacterial (LPS) or viral (P: IC) mimetics
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Article
25-Hydroxyvitamin D potentializes extracellular cathelicidin release from human PBMC stimulated ex vivo with either bacterial (LPS) or viral (P: IC) mimetics
Human cathelicidin refers to the cationic antimicrobial peptide hCAP18/LL-37. LL-37 is formed by cleavage of the propeptide hCAP18 coded by the CAMP gene. The active form of vitamin D, 1,25-dihydroxyvitamin D (1,...
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Article
Vitamin D supplementation associated with physical exercise promotes a tolerogenic immune environment without effect on mammary tumour growth in C57BL/6 mice
High plasma vitamin D (VitD) level and regular exercise (Ex) are known to have anti-cancer and immunomodulatory effects. This study aimed to evaluate the impact of VitD supplementation and imposed physical Ex ...
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Article
Open AccessEO771, the first luminal B mammary cancer cell line from C57BL/6 mice
Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatme...
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Article
Impact of basal diet on dextran sodium sulphate (DSS)-induced colitis in rats
Dextran sodium sulphate (DSS)-induced colitis is a widely used model for inflammatory bowel disease. However, various factors including nutrition may affect the development of this colitis. This study aimed t...
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Article
Open AccessVitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats
The diminished ability of aged muscle to self-repair is a factor behind sarcopenia and contributes to muscle atrophy. Muscle repair depends on satellite cells whose pool size is diminished with aging. A reduct...
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Article
Open AccessDoes aging affect the immune status? A comparative analysis in 300 healthy volunteers from France, Austria and Spain
As the European population is getting older, there is growing need in scientific data on how to achieve healthy and successful aging. A decline in immune function with age is unanimously supported by many epid...