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Article
Comparative Evaluation of the Pharmacological Activity of Fatty Aromatic Amides and Amines with a Framework Moiety and Their Non-Covalent Complexes
Pharmacological studies of the new fatty-aromatic amides, structural analogs of chlorobenzoylaminoadamantane (chlodantane), and non-covalent water-soluble complexes of chlodantane, adamantylbromophenylamine (b...
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Article
Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt
The mechanochemical preparation of solid compositions of praziquantel with plant saponin (glycyrrhizic acid disodium salt) is described. The study of a number of physicochemical parameters showed that dissolvi...
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Article
Gel chromatographic and toxicological studies of the mechanochemical transformations of water-soluble polysaccharides
Changes in the molecular weight characteristics of polysaccharide macromolecules - arabinogalactan, hydroxyethyl starch 200/0.5, Fibregum, and dextrans 10, 40, and 70 - were studied during mechanochemical proc...
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Article
Structural transformations of arabinogalactan from the Siberian larch during mechanochemical processing and the biological properties of the products
It has been found by gel-penetrating chromatography and quantitative 13C NMR spectroscopy that mechanochemical processing of arabinogalactan isolated from the wood of the Siberian larch changes the molecular mass...
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Article
Mechanical composites based on biologically active compounds from larch wood
Mechanical composites were prepared by mechanical chemical processing of a mixture of biologically active preparations of arabinogalactan (AG) and dihydroquercetin (DQ) isolated from larch wood. Their properti...
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Article
Mechanochemical preparation and pharmacological activities of water-soluble intermolecular complexes of arabinogalactan with medicinal agents
A possibility of mechanochemical preparation of water-soluble complexes of a plant polysaccharide arabinogalactan and poorly soluble medicinal agents (Sibazon(=Diazepam), Mezapam(=Medazepam), Indometacin, and ...