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    Article

    Fourier Transform Infrared Spectroscopic Characterization of Mineralizing Type I Collagen Enzymatic Trivalent Cross-Links

    The most abundant protein of bone’s organic matrix is collagen. One of its most important properties is its cross-linking pattern, which is responsible for the fibrillar matrices’ mechanical properties such as...

    E. P. Paschalis, S. Gamsjaeger, D. N. Tatakis, N. Hassler in Calcified Tissue International (2015)

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    Article

    Collagen Cross-Linking Influences Osteoblastic Differentiation

    Osteoblasts synthesize collagen matrix, which itself regulates the differentiation of precursor cells into mature osteoblasts. They express lysyl oxidase (LOX), which is involved in the collagen cross-linking ...

    C. Turecek, N. Fratzl-Zelman, M. Rumpler, B. Buchinger in Calcified Tissue International (2008)

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    Complementary Information on In Vitro Conversion of Amorphous (Precursor) Calcium Phosphate to Hydroxyapatite from Raman Microspectroscopy and Wide-Angle X-Ray Scattering

    In addition to mechanical functions, bones have an essential role in metabolic activity as mineral reservoirs that are able to absorb and release ions. Bioapatite, considered the major component in the mineral...

    M. Kazanci, P. Fratzl, K. Klaushofer, E. P. Paschalis in Calcified Tissue International (2006)

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    Osteoblast-Mediated Mineral Deposition in Culture is Dependent on Surface Microtopography

    Osteoblast phenotypic expression in monolayer culture depends on surface microtopography. Here we tested the hypothesis that mineralized bone nodule formation in response to osteotropic agents such as bone mor...

    B.D. Boyan, L.F. Bonewald, E.P. Paschalis, C.H. Lohmann in Calcified Tissue International (2002)

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    Article

    Optimal Methods for Processing Mineralized Tissues for Fourier Transform Infrared Microspectroscopy

    S. Aparicio, S.B. Doty, N.P. Camacho, E.P. Paschalis in Calcified Tissue International (2002)

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    Article

    FTIR Microspectroscopic Analysis of Human Iliac Crest Biopsies from Untreated Osteoporotic Bone

    Historically, osteoporosis has been defined as a disease in which there is ``too little bone, but what there is, is normal.'' As a result of research design and sample selection limitations, published data co...

    E. P. Paschalis, F. Betts, E. DiCarlo, R. Mendelsohn in Calcified Tissue International (1997)

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    FTIR Microspectroscopic Analysis of Normal Human Cortical and Trabecular Bone

    Fourier transform infrared microspectroscopy (FTIRM) has been used to study the changes in mineral and matrix content and composition in replicate biopsies of nonosteoporotic human cortical and trabecular bon...

    E. P. Paschalis, F. Betts, E. DiCarlo, R. Mendelsohn in Calcified Tissue International (1997)

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    FTIR microspectroscopic analysis of human osteonal bone

    Fourier Transform Infrared Microspectroscopy (FTIRM) has been used to study the changes in mineral and matrix content and composition in replicate biopsies of non-osteoporotic human osteonal bone. Spectral map...

    E. P. Paschalis, E. DiCarlo, F. Betts, P. Sherman in Calcified Tissue International (1996)

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    Fourier transform infrared spectroscopy of the solution-mediated conversion of amorphous calcium phosphate to hydroxyapatite: New correlations between X-ray diffraction and infrared data

    Fourier Transform infrared spectroscopic analysis of maturing, poorly crystalline hydroxyapatite (HA) formed from the conversion of amorphous calcium phosphate (ACP) at constant pH or variable pH show only sub...

    S. J. Gadaleta, E. P. Paschalis, F. Betts, R. Mendelsohn in Calcified Tissue International (1996)