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Article
Osteopontin Deficiency Increases Mineral Content and Mineral Crystallinity in Mouse Bone
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Article
Optimal Methods for Processing Mineralized Tissues for Fourier Transform Infrared Microspectroscopy
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Article
A Controlled Study of the Effects of Alendronate in a Growing Mouse Model of Osteogenesis Imperfecta
Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of the...
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Article
Dentin Sialoprotein (DSP) Has Limited Effects on In Vitro Apatite Formation and Growth
Sialoproteins such as bone sialoprotein (BSP) and dentin sialoprotein (DSP) accumulate at the mineralization fronts in bone and dentin, respectively, suggesting they have some function in the mineralization p...
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Article
Effects of Bone CS-Proteoglycans, DS-Decorin, and DS-Biglycan on Hydroxyapatite Formation in a Gelatin Gel
The small leucine-rich bone proteoglycans, biglycan and decorin, can be purified by chromatography on hydroxyapatite columns, demonstrating their potential affinities for bone apatite. To determine their effe...
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Article
Viable cells are a requirement forIn vitro cartilage calcification
It is a common belief that chondrocyte death must precede calcification in the growth plate. To challenge this dogma, cell devitalization was induced in anin vitro model that mimicsin situ cartilage calcification...
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Article
Ultrastructure and lysosomal histochemistry ofia rat osteoclasts
Histochemical techniques for light and electron microscopy showed that metaphyseal osteoclasts in “incisors absent” rats contained greater than normal amounts of lysosomal acid phosphatase, aryl sulfatase and ...
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Article
A method for obtaining ultrathin frozen sections from fresh or glutaraldehyde-fixed tissues
This paper describes a method for obtaining ultrathin frozen sections of fixed and unfixed tissues using a slightly modified LKB Cryokit. With these modifications, the specimen temperature is maintained at −18...