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  1. Article

    ACINO-INSULAR TRANSFORMATION IN PANCREASES OF CHILDREN WITH INTRACTABLE HYPERINSULINIC NEONATAL HYPOGLYCEMIA

    Marking by peroxidase-conjugated anti-insulin antibodies, and electron microscopy reveal in these pancreases, besides normal islets of Langerhans in lobular exocrine tissue -a/numerous insulin cells inside aci...

    B J Giron, E Hollande, C Lambre, H Lestradet in Pediatric Research (1975)

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    Article

    Histogenesis of the Endocrine pancreas in newborn rats after destruction by streptozotocin

    Endocrine pancreatic tissue in newborn rats was studied 1 to 17 days after the destruction of B cells by an injection of streptozotocin. Regeneration of insulin cells was observed four days after streptozotoci...

    D. Cantenys, B. Portha, M. C. Dutrillaux, E. Hollande, C. Rozé in Virchows Archiv B (1980)

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    Article

    Ultrastructural study of pancreatic B cell regeneration in newborn rats after destruction by streptozotocin

    An ultrastructural study of endocrine cells was performed in the pancreas of rats treated with a single dose of streptozotocin on the day of birth. Most of the B cells present at birth were destroyed by strept...

    M. C. Dutrillaux, B. Portha, C. Rozé, E. Hollande in Virchows Archiv B (1982)

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    Article

    Dissociation of Langerhans islets in the rabbit after pancreatic duct ligation

    In the rabbit, pancreatic duct ligation leads to serious disturbances of the pancreatic endocrine parenchyma. Immunocytochemical studies conducted over a short period (between 5 and 30 days post ligation) allo...

    J. Catala, R. Bonnafous, M. C. Dutrillaux, E. Hollande in Virchows Archiv B (1986)

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    Article

    Creatine phosphate as energy source in the cerulein-stimulated rat pancreas study by31P nuclear magnetic resonance

    Stimulation of the rat exocrine pancreas by cerulein induces a variety of cellular processes, some of which require the expenditure of energy. In this study, changes in the amounts of various energy metabolite...

    S. Aired, Y. Creach, C. Palevody, J. Esclassan in International journal of pancreatology (1991)

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    Article

    Anion channels in a human pancreatic cancer cell line (Capan-1) of ductal origin

    Transepithelial solute transport and bicarbonate secretion are major functions of pancreatic duct cells, and both functions are thought to involve the presence of chloride channels in the apical membrane of th...

    F. Becq, M. Fanjul, I. Mahieu, Z. Berger, M. Gola, E. Hollande in Pflügers Archiv (1992)

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    Article

    Characterization of a specific signal from human pancreatic tumors heterotransplanted into nude mice

    In a previous study, we demonstrated the existence of a 3.2 ± 0.2 ppm peak in the1H NMR spectrum at 60 MHz from human pancreatic adenocarcinomas (Capan-1 cell) heterotransplanted intonude mice. This peak, which i...

    C. Chemin-Thomas, J. Esclassan, C. Palevody in International journal of pancreatology (1993)

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    Article

    Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro

    The trypanocidal activity of naturally occurring 6-(3,4-dihydroxystyryl)-4-hydroxy-2-pyrone (hispidin) prompted us to examine its cytotoxic activity toward normal and cancerous cells in culture. Hispidin synth...

    C. Gonindard, C. Bergonzi, C. Denier, C. Sergheraert in Cell Biology and Toxicology (1997)

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    Article

    Evaluation of the effect of three calcium phosphate powders on osteoblast cells

    The aim of the present study was to assess the effect of three calcium phosphate powders entering in the composition of bone substitute materials on osteoblast-cells activity. These powders were hydroxyapatite...

    V. Midy, M. Dard, E. Hollande in Journal of Materials Science: Materials in Medicine (2001)

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    Article

    Adsorption of vascular endothelial growth factor to two different apatitic materials and its release

    The aim of our study was to assess the ability of calcium phosphate powders to serve as growth factor carriers. Vascular endothelial growth factor (VEGF), in particular, is locally involved in the bone formati...

    V. Midy, E. Hollande, C. Rey, M. Dard in Journal of Materials Science: Materials in… (2001)