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Article
Hypophyso-gonadal function in the diabetic child
Fourteen diabetic boys (five with family history of diabetes and nine without) and twenty-nine “short normal” boys were studied. A gonadal function test (2,000 IU of hCG im for three days and plasma testostero...
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Article
Effect of long term GH administration on the pituitary-thyroidal function in idiopathic hypopituitarism
24 euthyroidal children suffering from idiopathic pituitary dwarfism were studied. The thyroidal situation was evaluated through the assay of T3,T4 and the use of the TRH test.All of the children were treated ...
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Article
Sensitivity to exogenous insulin and endogenous insulin release in hypopituitary non-hypoglycemic children treated with HGH
35 hypopituitary patients treated with HGH, 5 hypopituitary subjects before the start of HGH treatment and 15 short-normal children were studied. Informed consent of the parents was obtained. In all the subjec...
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Article
Treatment of cryptorchidism by intrarasal syrthetic LH-RH analogue
The effect of ar aralogue of LH-RH (Ho 766,Hoechst) given by nasal spray to 20 cryptorchids was evaluated. 10 boys were treated with 100 μg (group A) and 10 boys with 25 μg (group B) of the analogue giver ever...
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Article
Prolactin secretion disorder in the obese prepubertal and pubertal boy
A disorder in the prolactin secretion has been demonstrated in the obese adult. No data of this kind exist concerning children.
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Article
Gonadal and adrenal secretion of dehydroepiandrosterone sulfate in prepubertal and pubertal subjects
The Authors have evaluated the relationship between the secretion of dehydroepiandrosterone sulfate (DHA-S) by the adrenal glands and by the gonads in a group of prepubertal and pubertal subjects (“short norma...
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Article
HLA genotypes and HLA-linked genetic markers in Italian patients with classical 21-hydroxylase deficiency
HLA genotype and HLA-linked marker data for 40 unrelated patients from central Italy and 2 unrelated patients from Sardinia with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21-OH-def) were...
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Article
Hypophyso-gonadal and hypophyso-adrenal function in boys with discordance between pubic hair and genital development
LH-RH tests (50 μg i.v.) and hCG tests (2000 IU/day for 3 days) were carried out in 16 normal boys in stage P1 both for genitalia and pubic hair (group 1); 7 normal boys over 91/2 years in stage P 1 for genitalia...
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Article
Neonatal screening for congenital-adrenal hyperplasia using a microfilter paper method for 17-α-hydroxyprogesterone radioimmunoassay. Experience gained from 22.233 cases
We examined 22.233 infants born in Emilia-Romagna (Italy). Capillary blood samples for 17-OH-progesterone assay were collected on the 3rd, 4th, 5th, 6th or 7th day of life on filter paper of the same type used...
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Article
Prolactin, TSH, T3, T4, fT3, fT4, TBG and reverse T3 in Turner's Syndrome
In 18 girls with Turner's S. basal plasma values of T3, T4, fT3, fT4, TBG and reverse T3 were assessed and a TRH-test carried out to assay prolactin and TSH. The results were studied bearing in mind the cariot...
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Article
Neonatal screening for 21-hydroxylase deficiency: a microfilter paper method for 17-α-hydroxyprogesterone assay
A micromethod for measuring 17a-hydroxyprogesterone in blo’od collected on filter paper has been developed. Our method is rapid, easy and has the specificity, accuracy and precisoin of the radioimmunoassay in ...
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Article
Treatment of cryptorchidism by intranasal synthetic LH-RH and its analogue d-ser(TBU)6-LHRH-EA10
Sixty-seven prepubertal boys with either uni- or bilateral cryptorchidism were treated with LH-RH or its analogue Hoe 766. In all cases the undescended testes were located in the inguinal canal; none had retra...
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Fibrinolysis and Body Weight: Fibrinolytic Response to Venous Occlusion in Obese Children
Obesity in adults is an important risk factor for cardiovascular diseases. An important role among these factors is played by some alterations in the mechanisms of coagulation. Changes in the fibrinolytic proc...
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Article
Somatomedin-C in fullterm, preterm and small for date infants
Capillary blood samples on filter paper were assayed by means of a RIA method (kit Nichols Institute USA) from 1096 newborns divided into fullterm,preterm and small for date infants.Somatomedin-C (SmC) mean va...
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Article
Haemorheologic and lipidemic parameters in obesity and diabetes
Haemorheologic and lipidemic tests were performed in 3 groups of children: 20 with obesity (14m,6f., age 11.4±2.6y) defined as a weight excess of at least 20% (OC) ; 16 with type 1 diabetes in compensated phas...
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Article
Some psychological aspects of young type-I-diabetics and of their parents
30 type-I-diabetic outpatients (15 m. and 15 f., mean age 11.5, range 7-17 yrs) and 47 healthy age-,sex-, and socioeconosically matched schoolchildren were submitted to the Louis Corman's family test. The diab...
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Article
Plasma Somatoiedin-C in children and adolescents with IDDM
Previous studies in diabetic patients have reported elevated normal and reduced somatomedin levels.We used RIA method to determine Somatomedin C (SMC) in 57 diabetic children and adolescents(29 f. and 28 m.;ag...
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Article
44 GH, HPRL, ACTH, TSH AND SmC RESPONSE TO GH-RF IN CHILDREN WITH PITUITARY DWARFISM
20 prepubertal GH-deficient children (C.A. 4.88-17.75yrs) were studied; 15 patients had isolated GH-deficiency, 5 had multiple pituitary hormone deficiencies, such as GH-ACTH-TSH (1 case), GH-TSH (2 cases), GH...
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Article
43 SHORT STATURE AND CELIAC DISEASE: CAN THE SIMPLE DETECTION OF THE ANTIBODIES TO GLIADIN RESOLVE THIS RELATIONSHIP?
107 nonselected children (77 n. and 30 f.) with short stature and absence of gastrointestinal tract symptoms were examined. In addition to the normal tests for the pathogenetic definition of short stature, in ...
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Article
45 SmC RESPONSE TO hGH AND GH-RF IN GH-RF-DEFICIENT CHILDREN
4 GH-RF deficient children (1 with isolated GH-deficiency, 2 with GH-TSH deficiencies, 1 with GH-TSH-ACTH-deficiencies) were administered s.c. hGH (after the previous hGH treatment had been discontinued 1 week...