2 Result(s)
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Donghoon Lee
Life Sciences
Computational Biology/Bioinformatics
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Article
Open AccessNIMBus: a negative binomial regression based Integrative Method for mutation Burden Analysis
Identifying frequently mutated regions is a key approach to discover DNA elements influencing cancer progression. However, it is challenging to identify these burdened regions due to mutation rate heterogeneit...
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Article
Open AccessDiNeR: a Differential graphical model for analysis of co-regulation Network Rewiring
During transcription, numerous transcription factors (TFs) bind to targets in a highly coordinated manner to control the gene expression. Alterations in groups of TF-binding profiles (i.e. “co-binding changes”...
