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    Article

    Hearing abnormalities in patients treated with teprotumumab

    The introduction of teprotumumab for the treatment of thyroid eye disease has dramatically improved management of this life-changing condition; however, clinical trials and experience in the clinic have reveal...

    Jason A. Brant, Don O. Kikkawa, Terry J. Smith in Nature Reviews Endocrinology (2024)

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    Article

    Role of muscle biopsy in diagnosis of extraocular muscles enlargement

    To study the role of muscle biopsy in patients with enlarged extraocular muscles.

    Mahmoud M. Abouelatta, Osama E. Shalaby, Amr M. Awara in International Ophthalmology (2023)

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    Article

    A new treatment modality for the enlarged extraocular muscles

    evaluation of the role of combined injection of triamcinolone acetonide with 5 Fluorouracil in treatment of the enlarged extraocular muscles secondary to chronic non-specific non-infectious inflammation.

    Mahmoud M. Abouelatta, Osama E. Shalaby, Amr M. Awara in International Ophthalmology (2023)

  4. No Access

    Chapter

    Management of Trichiasis

    Trichiasis, the abnormal inward rotation of the eyelashes, is a pathologic condition that commonly causes eye irritation. The treatment includes epilation, electrosurgical or thermal follicle destruction, and ...

    Mahmoud M. Abouelatta, Catherine Y. Liu in Plastic Surgery of the Lower Eyelids (2023)

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    Article

    Eyelid malignancies in young individuals: clinical peculiarities

    The incidence of malignant eyelid tumors is considerably increasing, even in young patients. The purpose of this study was to identify particularities in individuals under 40 years of age affected by eyelid ma...

    Débora F. Biazim, Midori H. Osaki, Don O. Kikkawa in International Ophthalmology (2022)

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    Chapter

    Surgical Approaches to the Orbit and Optic Nerve

    In 1888, Kronlein introduced the concept of lateral orbital rim removal to access deep orbital lesions. While this approach is still employed to this day, today’s aesthetically oriented orbital surgeon has a m...

    Ayelet Priel, Sang-Rog Oh, Don O. Kikkawa in Smith and Nesi’s Ophthalmic Plastic and Re… (2021)

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    Chapter

    Lower Eyelid Retraction: Middle/Posterior Lamellar Correction Using Autologous Grafts

    Lower eyelid retraction is a challenging complication associated with blepharoplasty. Understanding the preoperative and intraoperative risk factors for development will minimize complications and to design a ...

    Zvi Gur, Clara J. Men, Don O. Kikkawa in Avoiding and Managing Complications in Cos… (2020)

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    Chapter

    Introduction to Brow Lifting

    The brow and upper face undergo various changes with age resulting in brow ptosis and various other changes in the forehead and periocular region. This chapter reviews the differences in brow configuration bet...

    Bradford W. Lee, Brian C. Tse in Oculofacial, Orbital, and Lacrimal Surgery (2019)

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    Chapter

    Cutaneous Approaches to Brow Lifting

    The various cutaneous approaches to brow lifting all utilize excision of tissue to elevate the brows and in some cases rejuvenate the forehead. Each technique seeks to conceal the incision, whether at the junc...

    Bradford W. Lee, Ashley M. Crane in Oculofacial, Orbital, and Lacrimal Surgery (2019)

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    Chapter

    Orbital Decompression: Graded Surgical Approach

    Orbital decompression is an effective surgical intervention for the treatment of thyroid eye disease and other conditions causing expansion of orbital soft tissue volume. Indications for surgery include disfig...

    Kyle J. Godfrey, Christine C. Annunziata, Bobby S. Korn in Manual of Oculoplastic Surgery (2018)

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    Article

    Chemodenervation of extraocular muscles with botulinum toxin in thyroid eye disease

    Thyroid eye disease (TED) presents a management dilemma for strabismologists due to the variability of its clinical course. Prisms may be prescribed to relieve diplopia in small deviations. Surgical interventi...

    David B. Granet, Nickisa Hodgson in Graefe's Archive for Clinical and Experime… (2016)

  12. Article

    Open Access

    p16INK4A expression is frequently increased in periorbital and ocular squamous lesions

    p16 expression is a well established biomarker of cervical dysplasia and carcinoma arising from high risk human papilloma virus infection. Increased p16 expression is also seen in squamous neoplasms arising at...

    Peter J. Kobalka, Jean-Paul Abboud, **aoyan Liao, Karra Jones in Diagnostic Pathology (2015)

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    Chapter

    Complications of Ptosis Repair: Prevention and Management

    Ptosis repair is one of the most common operations in oculofacial plastic surgery. In mild cases, eyelid ptosis can be purely cosmetic, but in severe cases, it can cause significant visual field compromise, hi...

    Milad Hakimbashi, Don O. Kikkawa in Evaluation and Management of Blepharoptosis (2011)

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    Chapter

    Surgical Anatomy of the Forehead, Eyelids, and Midface for the Aesthetic Surgeon

    The eyes are probably our most important sensory organ, and eyelid surgery is one of the most common aesthetic procedures performed today. As such, it is incumbent upon the eyelid surgeon to become familiar an...

    Kevin S. Tan MD, Sang-Rog Oh MD in Master Techniques in Blepharoplasty and Pe… (2011)

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    Article

    Ballooning canaliculoplasty after lacrimal trephination in monocanalicular and common canalicular obstruction

    To evaluate the clinical effect of balloon canaliculoplasty with LacriCATH after lacrimal trephination in monocanalicular and common canalicular obstruction.

    Suk-Woo Yang, Hae-Young Park, Don O. Kikkawa in Japanese Journal of Ophthalmology (2008)

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    Article

    Stimulation of noradrenergic sympathetic outflow by calcitonin gene-related peptide

    Alternative splicing of RNA transcripts from the calcitonin gene produces mRNAs that encode different polypeptides1. While the mRNA encoding calcitonin predominates in thyroidal ‘C’ cells, calcitonin gene-related...

    Laurel A. Fisher, Don O. Kikkawa, Jean E. Rivier, Susan G. Amara, Ronald M. Evans in Nature (1983)