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Open AccessPOStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients (POSITiVE) II—study protocol of a randomized clinical trial
One single-center randomized clinical trial showed that INTELLiVENT-adaptive support ventilation (ASV) is superior to conventional ventilation with respect to the quality of ventilation in post-cardiac surgery...
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Open AccessSuccessful use of extracorporeal life support and hemadsorption in the context of venlafaxine intoxication requiring cardiopulmonary resuscitation: a case report
Venlafaxine is a serotonin and noradrenalin reuptake inhibitor prescribed as an antidepressant. Overdose clinically manifests with neurological, cardiovascular and gastrointestinal abnormalities based on, amon...
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Article
Open AccessOutcome, demography and resource utilization in ICU Patients with delirium and malignancy
Delirium in the general intensive care unit (ICU) population is common, associated with adverse outcomes and well studied. However, knowledge on delirium in the increasing number of ICU patients with malignanc...
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Article
Open AccessPulsatile arterial blood pressure mimicking aortic valve opening during continuous-flow LVAD support: a case report
Left ventricular assist devices (LVAD) have become a common treatment option in advanced heart failure. Lack of aortic valve opening during left ventricular unloading is a common complication and associated wi...
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Open AccessHeart rate elevations during early sepsis predict death in fluid-resuscitated rats with fecal peritonitis
In sepsis, early outcome prediction would allow investigation of both adaptive mechanisms underlying survival and maladaptive mechanisms resulting in death. The aim of this study was to test whether early chan...
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Open AccessA hospital-wide evaluation of delirium prevalence and outcomes in acute care patients - a cohort study
Delirium is a well-known complication in cardiac surgery and intensive care unit (ICU) patients. However, in many other settings its prevalence and clinical consequences are understudied. The aims of this stud...
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Article
Open AccessEffect of diagnosis related groups implementation on the intensive care unit of a Swiss tertiary hospital: a cohort study
In 2013 the Swiss Diagnosis Related Groups ((Swiss)-DRG) was implemented in Intensive Care Units (ICU). Its impact on hospitalizations has not yet been examined. We compared the number of ICU admissions, accor...
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Open AccessImproving animal welfare using continuous nalbuphine infusion in a long-term rat model of sepsis
Sepsis research relies on animal models to investigate the mechanisms of the dysregulated host response to infection. Animal welfare concerns request the use of potent analgesics for the Refinement of existing se...
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Open AccessIntra-operative events during cardiac surgery are risk factors for the development of delirium in the ICU
Risk factors for delirium following cardiac surgery are incompletely understood. The aim of this study was to investigate whether intra-operative pathophysiological alterations and therapeutic interventions in...
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Article
Open AccessImpact of cytokine release on ventricular function after hepatic reperfusion: a prospective observational echocardiographic study with tissue Doppler imaging
Postreperfusion syndrome and haemodynamic instability are predictors for poor outcome after liver transplantation. Cytokine release has been claimed to be responsible for postreperfusion syndrome. However, the...
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Cardiac output measurement in children: comparison of the Ultrasound Cardiac Output Monitor with thermodilution cardiac output measurement
To compare the assessment of cardiac output (CO) in children using the noninvasive Ultrasound Cardiac Output Monitor (USCOM) with the invasive pulmonary artery catheter (PAC) thermodilution cardiac output meas...
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Trauma of the Mediastinum
Pneumomediastinum, also known as mediastinal emphysema, refers to free air collections surrounding mediastinal structures [8, 21]. It occurs in up to 10% of blunt chest trauma [56]. In over ...
