Abstract
Pneumomediastinum, also known as mediastinal emphysema, refers to free air collections surrounding mediastinal structures [8, 21]. It occurs in up to 10% of blunt chest trauma [56]. In over 95% of cases, pneumomediastinum results either from extension of a subcutaneous emphysema or from alveolar rupture related to primary lung trauma or positive-pressure mechanical ventilation [56, 107, 108, 214, 260]. Alveolar rupture is followed by centripetal dissection of the released alveolar air through the pulmonary interstitium and along the peribroncho-vascular sheaths into the mediastinum; this pathophysiological process is classically described as the “Macklin effect” (Figs. 6.1,6.13) [31,159,288]. In the remaining cases, pneumomediastinum results from lesions of the trachea, bronchi or esophagus (Sects. 6.2,6.3) [56,108,214,260].
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Wintermark, M., Wicky, S., Bettex, D., Schnyder, P., Theumann, N. (2000). Trauma of the Mediastinum. In: Radiology of Blunt Trauma of the Chest. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57182-4_6
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