3 Result(s)
within
Dillon G. Patterson
English
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Article
Open AccessAntibody-secreting cell destiny emerges during the initial stages of B-cell activation
Upon stimulation, B cells assume heterogeneous cell fates, with only a fraction differentiating into antibody-secreting cells (ASC). Here we investigate B cell fate programming and heterogeneity during ASC dif...
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Article
Epigenetic programming underpins B cell dysfunction in human SLE
Systemic lupus erythematosus (SLE) is characterized by the expansion of extrafollicular pathogenic B cells derived from newly activated naive cells. Although these cells express distinct markers, their epigene...
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Article
Open AccessHuman snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion
Genetic searches for tumor suppressors have recently linked small nucleolar RNA misregulations with tumorigenesis. In addition to their classically defined functions, several small nucleolar RNAs are now known...
