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Open AccessAutoimmune Hepatitis: Serum Autoantibodies in Clinical Practice
Circulating autoantibodies are a key diagnostic tool in autoimmune hepatitis (AIH), being positive in 95% of the cases if tested according to dedicated guidelines issued by the International Autoimmune Hepatit...
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Open AccessAutoimmmune hepatitis
Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circu...
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Chapter
Autoimmune Liver Disease
Autoimmune liver disorders in childhood include autoimmune hepatitis (AIH), AIH/sclerosing cholangitis overlap syndrome (autoimmune sclerosing cholangitis, ASC), and AIH arising de novo after liver transplant.
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Open AccessLe malattie autoimmuni di fegato nell’adulto
L’epatite autoimmune è una infiammazione cronica del fegato che colpisce tutte le età, caratterizzata da transaminasi e immunoglobuline G elevate, presenza di autoanticorpi, epatite dell’interfaccia alla biops...
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Chapter
Adaptive Immunity and the Clinical Definition of Autoantibodies
Detection of autoantibodies in the patient’s serum is a key diagnostic tool in autoimmune liver diseases, provided that the clinician is familiar with the laboratory methods and interprets correctly the result...
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Chapter
Autoimmune Hepatitis
Autoimmune hepatitis (AIH) is a progressive inflammatory hepatopathy and an important cause of end-stage liver disease. Its aetiology remains unknown, though both genetic and environmental factors are involved...
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Chapter
Autoimmune Liver Disease
Juvenile autoimmune liver disease comprises autoimmune hepatitis (AIH) and autoimmune sclerosing cholangitis (ASC), characterized by liver inflammation, circulating autoantibodies and increased transaminase an...
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Article
Autoimmune hepatitis
Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide. The diagnosis of AIH relies on increased serum transaminase and immunoglobulin G levels, presence of autoantibod...
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Chapter
Autoimmune Liver Disease
Autoimmune liver disorders in childhood include autoimmune hepatitis (AIH), AIH/sclerosing cholangitis overlap syndrome (autoimmune sclerosing cholangitis, ASC) and AIH arising de novo after liver transplant.
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Autoimmune liver disease in Asian children
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Reference Work Entry In depth
Autoimmune Hepatitis
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Article
Autoimmune manifestations in viral hepatitis
Infections by the viruses responsible for hepatitis B, C and D are accompanied by a number of immunopathological manifestations. A link between infection and autoimmunity is particularly well documented for th...
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Article
Cutting Edge Issues in Autoimmune Hepatitis
Autoimmune hepatitis is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by circul...
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Article
Autoimmunity and Environment: Am I at risk?
The complex interplay between environmental factors and genetic susceptibility plays an essential role in disease pathogenesis. This is especially true for autoimmunity, where clinical reports, genomic and epi...
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Protocol
Human CD4+CD25highCD127low/neg Regulatory T Cells
CD4+CD25highCD127low/neg regulatory T cells (Tregs) play a critical role in the maintenance of peripheral tolerance and in controlling the development of autoimmune diseases. A combination of surface and intracel...
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Chapter
When and How to Treat the Pediatric Patient
Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder affecting mainly females, characterized serologically by high levels of transaminases and immunoglobulin G (IgG), and presence of autoant...
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Article
Autoimmune hepatitis
Autoimmune hepatitis (AIH) is a progressive inflammatory disorder that mainly affects females. It is a relatively rare but devastating disease that progresses rapidly unless immunosuppressive treatment is star...
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Article
Severity of the compensatory anti-inflammatory response determined by monocyte HLA-DR expression may assist outcome prediction in cirrhosis
To investigate variations in expression of the monocyte antigen presentation molecule HLA-DR in cirrhosis.
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Article
Autoimmune hepatitis
Autoimmune hepatitis (AIH) is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by ...
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Article
Biliary atresia
Biliary atresia (BA) is a condition unique to infancy. It results from inflammatory destruction of the intrahepatic and extrahepatic bile ducts. It is the most frequent surgically correctable liver disorder in...
