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Article
Endothelial Effects of 3-Hydroxyglutaric Acid: Implications for Glutaric Aciduria Type I
Infants with glutaric aciduria type 1 (GA1) are subject to intracranial vascular dysfunction. Here, we demonstrate that the disease-specific metabolite 3-hydroxyglutaric acid (3-OH-GA) inhibits basal and vascu...
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Article
High level of endostatin in epididymal epithelium: protection against primary malignancies in this organ?
Rete testis and epididymis are rare locations for primary tumors or metastasis. Assuming that this may be related to expression level of angiogenic inhibitors, we focused our study on the expression pattern of...
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Article
Endothelial and Hematopoietic Progenitor Cells (EPCs and HPCs): Hand in Hand Fate Determining Partners for Cancer Cells
Tumor growth and metastasis need new vessel formation by angiogenesis provided by mature endothelial cells and postnatal vasculogenesis provided by endothelial progenitor cells (EPCs). Emerging data suggest a ...
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Reference Work Entry In depth
Vascular Stabilization
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Article
Ex vivo and in vivo investigations of the novel 1,470 nm diode laser for potential treatment of benign prostatic enlargement
Perioperative haemorrhage is still the major complication of transurethral resection of the prostate (TURP) for benign enlargement of the prostate. Photoselective vaporisation of the prostate (PVP) with the po...
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Article
Ho:YAG-laser: treatment of vesicourethral strictures after radical prostatectomy
To review the indication, feasibility and treatment outcome of Ho:YAG laser application for definitive endoscopic treatment of anastomotic stricture formation after radical prostatectomy.
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Article
Nomogram aids clinical decision making after radical cystectomy
Accurate estimates of treatment success, complications and long-term morbidity are essential for patients to make informed medical decisions regarding treatment. Several multivariate prediction models have bee...
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Article
Radical cystectomy in the elderly patient: a contemporary comparison of perioperative complications in a single institution series
To report on our recent experience with peri- and postoperative morbidity of radical cystectomy in patients 75 years and older compared to younger patients.
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Reference Work Entry In depth
Vascular Stabilization
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Article
Tumor vessel stabilization and remodeling by anti-angiogenic therapy with bevacizumab
Bevacizumab-resistant tumor vessels were characterized by an increased vessel diameter and normalization of vascular structures by the recruitment of mature pericytes and smooth muscle cells. Here, we analyzed...
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Article
In vitro investigations of repulsion during laser lithotripsy using a pendulum set-up
Ureteroscopic laser lithotripsy is a commonly used technique to treat ureteral calculi.The type of energy source used is one of the main influences of retrograd calculi propulsion. Using a momentum pendulum un...
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Article
Does increasing the nodal yield improve outcomes in patients without nodal metastasis at radical cystectomy?
To determine whether the number of lymph nodes (LNs) examined is associated with outcomes in patients without nodal metastasis after radical cystectomy (RC).
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Article
Multicenter validation of the prognostic value of patient age in patients treated with radical cystectomy
Small studies have suggested that older patients have worse outcomes following radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB). We evaluated the association of patient age with clinical o...
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Article
Staging of muscle-invasive bladder cancer: can computerized tomography help us to decide on local treatment?
To assess the power of multi-detector row computerized tomography (MDCT) in daily routine as a basic staging procedure for the decision on local treatment of patients with bladder cancer.
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Article
Oncologic outcomes obtained after neoadjuvant and adjuvant chemotherapy for the treatment of urothelial carcinomas of the upper urinary tract: a review
Nephroureterectomy with excision of a bladder cuff is the gold standard in the treatment of upper urinary tract carcinomas (UTUC). But especially for patients suffering from advanced tumor stages, life expecta...
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Article
Does preoperative platelet count and thrombocytosis play a prognostic role in patients undergoing nephrectomy for renal cell carcinoma? Results of a comprehensive retrospective series
To evaluate the still controversially discussed prognostic role of preoperative platelet level (PPL) and thrombocytosis (TC) in patients who undergo surgery for renal cell carcinoma (RCC) based on the largest ...
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Article
Lessons learned from the International Renal Cell Carcinoma-Venous Thrombus Consortium (IRCC-VTC)
Renal cell carcinoma (RCC) extension into the renal vein or the inferior vena cava occurs in 4 %–10 % of all kidney cancer cases. This entity shows a wide range of different clinical and surgical scenarios, ma...
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Living Reference Work Entry In depth
Vascular Stabilization
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Article
Additional androgen deprivation makes the difference
The role of additional androgen deprivation therapy (ADT) in prostate cancer (PCa) patients treated with combined HDR brachytherapy (HDR-BT) and external beam radiotherapy (EBRT) is still unknown.
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Article
Surgical learning curve for open radical prostatectomy: Is there an end to the learning curve?
To analyze the impact of surgeon’s experience on surgical margin status, postoperative continence and operative time after radical prostatectomy (RP) in a surgeon who performed more than 2000 open RP.
