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  1. Article

    Open Access

    Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis

    Within endemic regions in southern and eastern Germany, Borna disease virus 1 (BoDV-1) causes rare zoonotic spill-over infections in humans, leading to encephalitis with a high case-fatality risk. So far, intra-v...

    Markus Bauswein, Ehab Eid, Lisa Eidenschink, Barbara Schmidt, André Gessner in Infection (2024)

  2. Article

    Open Access

    Detection of bornavirus-reactive antibodies and BoDV-1 RNA only in encephalitis patients from virus endemic areas: a comparative serological and molecular sensitivity, specificity, predictive value, and disease duration correlation study

    Human Borna disease virus (BoDV-1) encephalitis is an emerging disease in Germany. This study investigates the spectrum of human BoDV-1 infection, characterizes anti-BoDV-1-antibodies and kinetics, and compare...

    Petra Allartz, Sven-Kevin Hotop, Birgit Muntau, Alexander Schlaphof in Infection (2024)

  3. Article

    Open Access

    Seroprevalence of arthropod-borne bacterial infections in homeless individuals in Hamburg in 2020

    The number of homeless people in Germany is steadily increasing. Due to their often precarious living conditions, this specific population may be increasingly exposed to ectoparasites that can transmit various...

    Fabian Heinrich, Jessica Rauch, Franziska Bertram, Volkhard A. J. Kempf in Infection (2023)

  4. Article

    Open Access

    First detected geographical cluster of BoDV-1 encephalitis from same small village in two children: therapeutic considerations and epidemiological implications

    The Borna disease virus (BoDV-1) is an emerging zoonotic virus causing severe and mostly fatal encephalitis in humans.

    Leonie Grosse, Victoria Lieftüchter, Yannik Vollmuth, Florian Hoffmann in Infection (2023)

  5. Article

    Open Access

    Cerebral Taenia crassiceps larvae infection in a 71-year-old immunocompetent male

    We report a rare case of a cerebral infection with Taenia crassiceps tapeworm larvae in an immunocompetent 71-year-old German male. Initially, an intracerebral malignoma was suspected after the patient experience...

    Niklas Floß, Sebastian Dolff, Andreas Junker, Tobias Blau, Laurel Rauschenbach in Infection (2023)

  6. Article

    Open Access

    Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report

    The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany.

    Dennis Tappe, Kirsten Pörtner, Christina Frank, Hendrik Wilking in BMC Infectious Diseases (2021)

  7. Article

    Open Access

    Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

    Human encephalitis can originate from a variety of different aetiologies, of which infection is the most common one. The diagnostic work-up is specifically challenging in patients with travel history since a b...

    Andreas Osterman, Viktoria C. Ruf, Cristina Domingo in BMC Infectious Diseases (2020)

  8. No Access

    Article

    Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center

    To determine epidemiological, clinical and laboratory characteristics of leptospirosis, 24 consecutive patients diagnosed with the infection between 2011 and 2017 at the University Medical Center Hamburg-Eppen...

    Thomas Theo Brehm, Julian Schulze zur Wiesch, Marc Lütgehetmann, Dennis Tappe in Infection (2018)