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  1. No Access

    Article

    Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples

    The B-cell lymphoma-2 (Bcl-2) family contains six antiapoptotic members, each with a hydrophobic pocket in which Bcl-2 homology region 3 (BH3) helices bind. This binding quenches apoptotic signals from activat...

    Peter C Simons, Susan M Young, Mark B Carter, Anna Waller, Dayong Zhai… in Nature Protocols (2011)

  2. No Access

    Article

    Dependence of permeability transition pore opening and cytochrome C release from mitochondria on mitochondria energetic status

    The dependence of Ca2+-induced permeability transition pore (PTP) opening and cytochrome c (Cyt. c) release from mitochondria on mitochondria energetic status was investigated. Results of test the PTP opening and...

    **ngxu Huang, Dayong Zhai, Youguo Huang in Molecular and Cellular Biochemistry (2001)

  3. No Access

    Article

    Study on the relationship between calcium-induced calcium release from mitochondria and PTP opening

    The permeability transition pore (PTP) is central for mitochondria function. PTP either open in low-conductance state to carry out mCICR (Ca2+-induced Ca2+ release from mitochondria) and play roles in cell phsyio...

    **ngxu Huang, Dayong Zhai, Youguo Huang in Molecular and Cellular Biochemistry (2000)