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  1. No Access

    Article

    Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples

    The B-cell lymphoma-2 (Bcl-2) family contains six antiapoptotic members, each with a hydrophobic pocket in which Bcl-2 homology region 3 (BH3) helices bind. This binding quenches apoptotic signals from activat...

    Peter C Simons, Susan M Young, Mark B Carter, Anna Waller, Dayong Zhai… in Nature Protocols (2011)

  2. No Access

    Article

    Humanin peptide suppresses apoptosis by interfering with Bax activation

    Bax (Bcl2-associated X protein) is an apoptosis-inducing protein that participates in cell death during normal development and in various diseases1. Bax resides in an inactive state in the cytosol of many cells. ...

    Bin Guo, Dayong Zhai, Edelmira Cabezas, Kate Welsh, Shahrzad Nouraini… in Nature (2003)

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    Article

    Dependence of permeability transition pore opening and cytochrome C release from mitochondria on mitochondria energetic status

    The dependence of Ca2+-induced permeability transition pore (PTP) opening and cytochrome c (Cyt. c) release from mitochondria on mitochondria energetic status was investigated. Results of test the PTP opening and...

    **ngxu Huang, Dayong Zhai, Youguo Huang in Molecular and Cellular Biochemistry (2001)

  4. No Access

    Article

    Study on the relationship between calcium-induced calcium release from mitochondria and PTP opening

    The permeability transition pore (PTP) is central for mitochondria function. PTP either open in low-conductance state to carry out mCICR (Ca2+-induced Ca2+ release from mitochondria) and play roles in cell phsyio...

    **ngxu Huang, Dayong Zhai, Youguo Huang in Molecular and Cellular Biochemistry (2000)