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Article
A whole population analysis of sex-specific anatomic differences in melanoma: rising melanoma in situ on the legs and trunk in females
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Article
Open AccessAuthor Correction: Drought re-routes soil microbial carbon metabolism towards emission of volatile metabolites in an artificial tropical rainforest
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Article
Open AccessDrought re-routes soil microbial carbon metabolism towards emission of volatile metabolites in an artificial tropical rainforest
Drought impacts on microbial activity can alter soil carbon fate and lead to the loss of stored carbon to the atmosphere as CO2 and volatile organic compounds (VOCs). Here we examined drought impacts on carbon al...
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Article
Open AccessCorrection to: Microbial colonization and persistence in deep fractured shales is guided by metabolic exchanges and viral predation
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Article
Open AccessMicrobial colonization and persistence in deep fractured shales is guided by metabolic exchanges and viral predation
Microbial colonization of subsurface shales following hydraulic fracturing offers the opportunity to study coupled biotic and abiotic factors that impact microbial persistence in engineered deep subsurface eco...
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Article
Open AccessDecrypting bacterial polyphenol metabolism in an anoxic wetland soil
Microorganisms play vital roles in modulating organic matter decomposition and nutrient cycling in soil ecosystems. The enzyme latch paradigm posits microbial degradation of polyphenols is hindered in anoxic p...
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Article
Open AccessTemporospatial shifts in the human gut microbiome and metabolome after gastric bypass surgery
Although the etiology of obesity is not well-understood, genetic, environmental, and microbiome elements are recognized as contributors to this rising pandemic. It is well documented that Roux-en-Y gastric byp...
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Article
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria
It is generally believed that exchange of secondary metabolite biosynthetic gene clusters (BGCs) among closely related bacteria is an important driver of BGC evolution and diversification. Applying this idea m...
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Article
Viruses control dominant bacteria colonizing the terrestrial deep biosphere after hydraulic fracturing
The deep terrestrial biosphere harbours a substantial fraction of Earth’s biomass and remains understudied compared with other ecosystems. Deep biosphere life primarily consists of bacteria and archaea, yet kn...
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Article
Open AccessInterspecies cross-feeding orchestrates carbon degradation in the rumen ecosystem
Because of their agricultural value, there is a great body of research dedicated to understanding the microorganisms responsible for rumen carbon degradation. However, we lack a holistic view of the microbial ...
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Reference Work Entry In depth
Development and Application of In Situ High-Temperature, High-Pressure Magic Angle Spinning NMR
Solid-state NMR has served as an important tool for investigating chemical systems, not only to better understand the structure of materials, but also to probe the interactions that occur between two or more c...
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Article
Open AccessMethanogenesis in oxygenated soils is a substantial fraction of wetland methane emissions
The current paradigm, widely incorporated in soil biogeochemical models, is that microbial methanogenesis can only occur in anoxic habitats. In contrast, here we show clear geochemical and biological evidence ...
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Living Reference Work Entry In depth
Development and Application of In Situ High-Temperature, High-Pressure Magic Angle Spinning NMR
Solid-state NMR has served as an important tool for investigating chemical systems, not only to better understand the structure of materials, but also to probe the interactions that occur between two or more c...
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Article
Open AccessMicrobial metabolisms in a 2.5-km-deep ecosystem created by hydraulic fracturing in shales
Hydraulic fracturing is the industry standard for extracting hydrocarbons from shale formations. Attention has been paid to the economic benefits and environmental impacts of this process, yet the biogeochemic...
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Article
Expanding your laboratory by accessing collaboratory resources
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Chapter
Lucent Technologies: Achieving the “Impossible” by Using Provisioning and Postponement
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Chapter
Characterization of Transforming Growth Factor Alpha binding to Epidermal Growth Factor receptor through NMR structure determination and NOE analysis methods
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Article
Structure of a BRCA1–BARD1 heterodimeric RING–RING complex
The RING domain of the breast and ovarian cancer tumor suppressor BRCA1 interacts with multiple cognate proteins, including the RING protein BARD1. Proper function of the BRCA1 RING domain is critical, as evid...
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Article
Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein
BAG-family proteins share a conserved protein interaction region, called the 'BAG domain', which binds and regulates Hsp70/Hsc70 molecular chaperones. This family of cochaperones functionally regulates signal ...