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  1. Article

    Open Access

    The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation

    The TIR domain-containing proteins BtpA/Btp1/TcpB and BtpB are translocated into host cells by the facultative intracellular bacterial pathogen Brucella. Here, they interfere with Toll like receptor signalling to...

    Christine Felix, Burcu Kaplan Türköz, Sebastien Ranaldi… in Cell Communication and Signaling (2014)

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    Brucella

    Brucellosis affects millions of animals and humans world-wide; in humans, over 500,000 new cases are reported annually. Although some vaccines are available for its prevention in animals, none exist for humans...

    Nammalwar Sriranganathan, Mohamed N. Seleem… in Genome Map** and Genomics in Animal-Asso… (2009)

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    The evolution of chronic infection strategies in the α-proteobacteria

    The α-subdivision of the Proteobacteria is a very large and diverse group of Gram-negative microorganisms. They show great variability in metabolic capacities and inhabit diverse ecological niches. The authors...

    Jacques Batut, Siv G. E. Andersson, David O'Callaghan in Nature Reviews Microbiology (2004)

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    Article

    High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation

    Salmonella typhimurium and S. typhi were transformd with high efficiency by electroporation. Transformation efficiencies of up to 1010 transformants per μg of pBR322 were obtained. In contrast to chemical transf...

    David O'Callaghan, Alain Charbit in Molecular and General Genetics MGG (1990)

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    Article

    Oral vaccination

    Gordon Dougan, Duncan Maskell, David O'Callaghan… in Antonie van Leeuwenhoek (1988)