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Article
Open AccessThe impact of trained radiographers as concurrent readers on performance and reading time of experienced radiologists in the UK Lung Cancer Screening (UKLS) trial
To compare radiologists’ performance reading CTs independently with their performance using radiographers as concurrent readers in lung cancer screening.
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Article
Imaging aspects of the diagnosis of sarcoidosis
Sarcoidosis is a systemic granulomatous disorder of unknown aetiology with a wide spectrum of radiological appearances and almost invariably pulmonary involvement. Lung involvement accounts for most of the mor...
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Article
Chronic hypersensitivity pneumonitis: high resolution computed tomography patterns and pulmonary function indices as prognostic determinants
To investigate high resolution computed tomography (HRCT) and pulmonary function indices (PFTs) for determining prognosis in patients with chronic fibrotic hypersensitivity pneumonitis (CHP).
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Article
European and North American lung cancer screening experience and implications for pulmonary nodule management
The potential for low dose computed tomography (LDCT) to act as an effective tool in screening for lung cancer is currently the subject of several randomised control trials. It has recently been given prominen...
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Article
Organizing pneumonia: a kaleidoscope of concepts and morphologies
The basic histopathological pattern of organizing pneumonia (OP) is well recognized, but the contexts in which it is encountered continue to increase. In parallel with an appreciation of new causes and associa...
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Article
Fibrotic idiopathic interstitial pneumonias: HRCT findings that predict mortality
The study aims were to identify CT features that predict outcome of fibrotic idiopathic interstitial pneumonia (IIP) when information from lung biopsy data is unavailable.
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Article
Diffuse interstitial lung disease: overlaps and uncertainties
Histopathological analysis of lung biopsy material allows the diagnosis of idiopathic interstitial pneumonias; however, the strength of this diagnosis is sometimes subverted by interobserver variation and samp...
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Article
Bronchial diverticula in smokers on thin-section CT
The objective was to determine the prevalence of bronchial diverticula in smokers on thin-section CT and the relationship to clinical and other morphological features on CT. Thin-section CT images of 503 cigar...
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Article
Open AccessNon-specific interstitial pneumonia in cigarette smokers: a CT study
The goal of this study was to seek indirect evidence that smoking is an aetiological factor in some patients with non-specific interstitial pneumonia (NSIP). Ten current and eight ex-smokers with NSIP were com...
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Reference Work Entry In depth
Interstitial Lung Diseases, Known Causes or Association
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Reference Work Entry In depth
Interstitial Lung Diseases, Unknown Etiology
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Chapter
Smoking-Related Small Airways and Interstitial Lung Disease
The consequences of airways and interstitial inflammation caused by cigarette smoking are many and varied. In addition to well-recognized smoking-related disorders, including chronic bronchitis and emphysema, ...
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Article
Quantification of emphysema: a composite physiologic index derived from CT estimation of disease extent
The combination of functional indices best reflecting the extent of emphysema is not known. High-resolution computed tomography (HRCT) studies of 106 patients with emphysema [men=71; median age=61 (range=26–86...
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Article
Imaging of macrophage-related lung diseases
Macrophage-related pulmonary diseases are a heterogeneous group of disorders characterized by macrophage accumulation, activation or dysfunction. These conditions include smoking-related interstitial lung dise...
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Chapter
HRCT — Pathologic Correlations in Small Airways Diseases
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Article
Traction bronchiectasis in cryptogenic fibrosing alveolitis: associated computed tomographic features and physiological significance
Our objective was to evaluate the associated CT features and physiological consequences of traction bronchiectasis in patients with cryptogenic fibrosing alveolitis (CFA). The CT scans of 212 patients with CFA...
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Article
Aspergillus in the lung: diverse and coincident forms
Pulmonary disease caused by the fungus Aspergillus has traditionally been regarded as belonging to one of the following, apparently distinct, entities: saprophytic aspergilloma; allergic bronchopulmonary aspergil...
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Article
Loss of FEV1 in cystic fibrosis: correlation with HRCT features
The purpose of this study was to determine which high-resolution computed tomography (HRCT) features in patients with cystic fibrosis are most strongly associated with functional impairment as expressed by fo...
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Article
Organizing pneumonia: the many morphological faces
Organizing pneumonia is a non-specific response to various forms of lung injury and is the pathological hallmark of the distinct clinical entity termed cryptogenic organizing pneumonia. The typical imaging fe...
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Article
Idiopathic interstitial pneumonias: imaging–pathology correlation
The terminology related to idiopathic interstitial pneumonia (IIP) remains confusing and in some cases wholly inaccurate. In addition, a greater understanding of the correlation between high-resolution comput...