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within David Gatfield Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter English Remove this filter

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  1. No Access

    Article

    An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay

    The specification of both the germ line and abdomen in Drosophila depends on the localization of oskar messenger RNA to the posterior of the oocyte1,2. This localization requires several trans-acting factors, inc...

    Isabel M. Palacios, David Gatfield, Daniel St Johnston, Elisa Izaurralde in Nature (2004)

  2. No Access

    Article

    Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

    In eukaryotic cells, messenger RNAs harbouring premature termination codons (PTCs) are rapidly degraded by a conserved post-transcriptional mechanism referred to as nonsense-mediated mRNA decay (NMD)1,2, which pr...

    David Gatfield, Elisa Izaurralde in Nature (2004)

  3. No Access

    Article

    Transcriptome and translatome co-evolution in mammals

    Gene-expression programs define shared and species-specific phenotypes, but their evolution remains largely uncharacterized beyond the transcriptome layer1. Here we report an analysis of the co-evolution of trans...

    Zhong-Yi Wang, Evgeny Leushkin, Angélica Liechti, Svetlana Ovchinnikova… in Nature (2020)