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    Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

    The clinical translation of cationic α-helical antimicrobial peptides (AMPs) has been hindered by structural instability, proteolytic degradation and in vivo toxicity from nonspecific membrane lysis. Although ...

    Rida Mourtada, Henry D. Herce, Daniel J. Yin, Jamie A. Moroco… in Nature Biotechnology (2019)