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Chapter
Treatment of Facial Asymmetry with Botulinum Toxin
Facial asymmetry is an almost universal feature, but can also be a manifestation of numerous conditions that affect all of the anatomical facial planes. Asymmetry attributed to imbalance of muscle activity can...
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Chapter
Floppy Eyelid Syndrome
Floppy Eyelid Syndrome is an enigmatic condition characterised by loss of elasticity of the tarsal plate, papillary conjunctivitis and eversion of the eyelid at nighttime. Since the condition was first describ...
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Chapter
Lacrimal By-Pass Surgery
The use of Lester Jones bypass tubes remains an important treatment modality for complex lacrimal outflow obstruction that cannot be addressed with other forms of lacrimal surgery. It is particularly effective...
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Chapter
Essential Blepharospasm
Benign essential blepharospasm (BEB) is a focal facial dystonia characterised by involuntary forced eyelids closure due to periorbital and facial muscle spasm. Over the last decades, the complex underlying mec...
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Article
Safety and efficacy of subcutaneous diode laser as a novel treatment in the management of festoons
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Article
Blood-stained tears—a red flag for malignancy?
Blood-stained tears can indicate occult malignancy of the lacrimal drainage apparatus. This study reviews data on patients presenting with blood in their tears and the underlying cause for this rare symptom.
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Article
Introducing the ‘Benign Eyelid Lesion Pathway’: 1 year experience of synchronous tele-oculoplastics in a tertiary hospital
Patients with benign eyelid lesions make up a large proportion of referrals to the oculoplastic service and lend themselves well to telemedicine with assessments heavily reliant on history, observation-based e...
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Article
Open AccessA patient-initiated treatment model for blepharospasm and hemifacial spasm: a randomized controlled trial
To test, in a two-arm, single center, superiority, randomized controlled trial, the effectiveness of and costs associated with a patient-initiated treatment model for people with hemifacial spasm (HFS) and ble...
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Article
Open AccessRecurrent epiphora after dacryocystorhinostomy surgery: Structural abnormalities identified with dacryocystography and long term outcomes of revision surgery
To investigate the aetiopathology of recurrent epiphora or stickiness after dacryocystorhinostomy (DCR) surgery, identifiable on dacryocystography (DCG), and to assess the success rates of secondary corrective...
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Article
Open AccessTeprotumumab: a disease modifying treatment for graves’ orbitopathy
On 21st January 2020, the FDA approved Tepezza (teprotumumab-trbw) for the treatment of active Graves’ orbitopathy (GO) in adults. This approval was based on positive results from two multinational randomised ...
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Article
New insights into the pathogenesis and nonsurgical management of Graves orbitopathy
Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is visually disabling, cosmetically disfiguring and has a substantial negative impact on a patient’s quality of life. Th...
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Article
Open AccessMacrophages promote a profibrotic phenotype in orbital fibroblasts through increased hyaluronic acid production and cell contractility
Graves’ orbitopathy (GO) is an autoimmune inflammatory disease affecting the orbit. Orbital fibroblasts are a key component in GO pathogenesis, which includes inflammation, adipogenesis, hyaluronic acid (HA) s...
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Article
Open AccessMicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma
Sebaceous gland carcinoma (SGC) is a rare, but life-threatening condition with a predilection for the periocular region. Eyelid SGC can be broadly categorised into two subtypes, namely either nodular or pageto...
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Article
Open AccessErratum to: ‘Effectiveness and cost-effectiveness of a patient-initiated botulinum toxin treatment model for blepharospasm and hemifacial spasm compared to standard care: study protocol for a randomised controlled trial’
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Article
Open AccessFibroblasts profiling in scarring trachoma identifies IL-6 as a functional component of a fibroblast-macrophage pro-fibrotic and pro-inflammatory feedback loop
Trachoma is a conjunctiva scarring disease, which is the leading infectious cause of blindness worldwide. Yet, the molecular mechanisms underlying progressive fibrosis in trachoma are unknown. To investigate t...
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Article
Open AccessEffectiveness and cost-effectiveness of a patient-initiated botulinum toxin treatment model for blepharospasm and hemifacial spasm compared to standard care: study protocol for a randomised controlled trial
Blepharospasm and hemifacial spasm are debilitating conditions that significantly impact on patient quality of life. Cyclical treatment with botulinum toxin injections offers temporary relief, but the duration...
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Article
Open AccessRetro-orbital oedema and transient blindness following endoscopic oesophagogastroduodenoscopy: a case report
This case report looks at the association of an endoscopic oesophagogastroduodenoscopy and the onset of retro-orbital oedema in a young female. A literature search was performed in order to find any common fac...
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Article
Randomised trial comparing ocular lubricants and polyacrylamide hydrogel dressings in the prevention of exposure keratopathy in the critically ill
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Article
Randomised trial comparing ocular lubricants and polyacrylamide hydrogel dressings in the prevention of exposure keratopathy in the critically ill
To compare the cost and effectiveness of the two most popular forms of eye care in intensive care, ocular lubricant (Lacrilube) and polyacrylamide hydrogel dressings (Geliperm); for the prevention of exposure ...
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Article
Assessment of corneal epitheliopathy in the critically ill
