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Article
Numerical analysis on the impact response of stone masonry arches with a GPGPU-parallelised FDEM
Stone masonry arches are composed of voussoirs, and they exhibit highly nonlinear and discontinuous characteristics under impact. A three-dimensional GPGPU-parallelised combined (hybrid) finite-discrete elemen...
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Article
Experimental and numerical studies on dynamic fracturing behavior of roughly jointed rock
The surface roughness is an important feature of rock joints. Its effect on the mechanical properties of joints is significant in characterizing dynamic failure of natural rock masses. Both laboratory experime...
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Article
Open AccessFundamental diagram of urban rail transit considering train–passenger interaction
Urban rail transit often operates with high service frequencies to serve heavy passenger demand during rush hours. Such operations can be delayed by two types of congestion: train congestion and passenger cong...
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Article
Open AccessPolymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy
Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy. However, ...
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Article
Simulation-based joint optimization framework for congestion mitigation in multimodal urban network: a macroscopic approach
Travel demand management (TDM) is an important measure that will aid in the realization of efficient and sustainable transportation systems. However, in cities where the most serious traffic congestion occurs,...
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Article
Laboratory Investigation on the Permeability Variation of Fractured Inada Granite by Multiple Transient Axial Stress Disturbances
A persistent increase in the permeability of rock mass caused by transient stress disturbances could explain the variation in groundwater level caused by earthquakes in the far-fields, increase in petroleum pr...
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Article
Cross Comparison of Spatial Partitioning Methods for an Urban Transportation Network
Partitioning a heterogeneous road network into homogenous subnetworks is one way of solving the problem of high scattering or a hysteresis loop that may be inherent in the empirics of a macroscopic fundamental...
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Article
Development of a 3D Hybrid Finite-Discrete Element Simulator Based on GPGPU-Parallelized Computation for Modelling Rock Fracturing Under Quasi-Static and Dynamic Loading Conditions
As a state-of-the-art computational method for simulating rock fracturing and fragmentation, the combined finite-discrete element method (FDEM) has become widely accepted since Munjiza (2004) published his compre...
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Article
Open AccessWater drainage from Kushiro Coal Mine decreased on the day of all M ≥ 7.5 earthquakes and increased thereafter
The amount of water drainage from Kushiro Coal Mine in Hokkaido, Japan decreased on the day of all M ≥ 7.5 earthquakes with epicenters within 300 km of the mine during the monitoring period and increased after th...
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Article
Permeability of Granite Including Macro-Fracture Naturally Filled with Fine-Grained Minerals
Information on the permeability of rock is essential for various geoengineering projects, such as geological disposal of radioactive wastes, hydrocarbon extraction, and natural hazard risk mitigation. It is es...
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Article
Self-Fulfilling Signal of an Endogenous State in Network Congestion Games
We consider the problem of coordination via signaling in network congestion games to improve social welfare deteriorated by incomplete information about traffic flow. Traditional studies on signaling, which fo...
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Article
Ogipeptins, novel inhibitors of LPS: physicochemical properties and structural elucidation
In the course of our screening program for inhibitors of lipopolysaccharide binding to cellular receptor CD14, a potent inhibitory activity was detected in the cultured broth of Pseudoalteromonas sp. SANK 71903. ...
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Article
Identification and biological activity of ogipeptins, novel LPS inhibitors produced by marine bacterium
A library of secondary metabolites from microorganisms was screened to identify novel inhibitors against lipopolysaccharide (LPS), a strong stimulant of innate immunity. Novel cyclic peptides, ogipeptin A, B, ...
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Article
Fractured Rock Permeability as a Function of Temperature and Confining Pressure
Triaxial compression tests were carried out on Shikotsu welded tuff, Kimachi sandstone, and Inada granite under confining pressures of 1–15 MPa at 295 and 353 K. The permeability of the tuff declined monotonic...
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Article
Observation of fracture sealing in high-strength and ultra-low-permeability concrete by micro-focus X-ray CT and SEM/EDX
Fracture sealing by precipitation is known to occur in high-strength and ultra-low-permeability concrete (HSULPC) immersed in water. Because a high ability to retard radionuclide migration is required for HSUL...
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Article
Screening and biological activities of pedopeptins, novel inhibitors of LPS produced by soil bacteria
Lipopolysaccharide (LPS) is a strong endotoxin and is delivered to the cell surface signaling receptor, Toll-like receptor 4 and MD-2 complex, via soluble cluster of differentiation (CD) 14 or membranous CD14,...
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Article
Pedopeptins, novel inhibitors of LPS: Taxonomy of producing organism, fermentation, isolation, physicochemical properties and structural elucidation
In the course of our screening for inhibitors of lipopolysaccharide (LPS) binding to cellular receptor CD14, potent inhibitory activity was detected in the cultured broth of Pedobacter sp. SANK 72003. Three activ...
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Chapter and Conference Paper
An Econometric-based Model of Pedestrian Walking Behavior Implicitly Considering Strategic or Tactical Decisions
We propose an econometric-based model for the behavior of pedestrian walking that implicitly considers strategic or tactical decisions. In real situations, it is only possible to observe pedestrian trajectorie...
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Chapter
The Extent of Biodiversity Recovery During Reforestation After Swidden Cultivation and the Impacts of Land-Use Changes on the Biodiversity of a Tropical Rainforest Region in Borneo
Whereas many studies have addressed the effects of deforestation on biodiversity, few have focused on the recovery of diversity during reforestation. This study aimed at evaluating the recovery of, or chronose...
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Article
Numerical simulation of the fracture process in concrete resulting from deflagration phenomena
This paper investigated the mechanism of fracture in concrete due to the deflagration phenomenon. For this purpose, the electric discharge impulse crushing method was selected, with liquid nitromethane (NM) ta...
